|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0033684,
umls-concept:C0079925,
umls-concept:C0086418,
umls-concept:C0220825,
umls-concept:C0439851,
umls-concept:C0441655,
umls-concept:C0599533,
umls-concept:C0600531,
umls-concept:C1334098,
umls-concept:C1552596,
umls-concept:C1704222,
umls-concept:C1707689,
umls-concept:C1947931
|
|
pubmed:issue |
8
|
|
pubmed:dateCreated |
1999-11-1
|
|
pubmed:abstractText |
The two objectives of this study were to design potent phosphorothioate antisense oligonucleotides (AS-S-oligos) directed against the human interleukin-10 (IL-10) gene product and to reveal the DNA sequence which best activates antisense effects.
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Aug
|
|
pubmed:issn |
0724-8741
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
16
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
1163-71
|
|
pubmed:dateRevised |
2007-11-15
|
|
pubmed:meshHeading |
pubmed-meshheading:10468015-Drug Design,
pubmed-meshheading:10468015-Evaluation Studies as Topic,
pubmed-meshheading:10468015-Humans,
pubmed-meshheading:10468015-Interleukin-10,
pubmed-meshheading:10468015-Nucleic Acid Conformation,
pubmed-meshheading:10468015-Nucleic Acid Hybridization,
pubmed-meshheading:10468015-Oligonucleotides, Antisense,
pubmed-meshheading:10468015-RNA, Messenger,
pubmed-meshheading:10468015-Thionucleotides,
pubmed-meshheading:10468015-Tumor Necrosis Factor-alpha,
pubmed-meshheading:10468015-U937 Cells
|
|
pubmed:year |
1999
|
|
pubmed:articleTitle |
Design of potent phosphorothioate antisense oligonucleotides directed to human interleukin 10 gene product and their evaluation of antisense activity in U937 cells.
|
|
pubmed:affiliation |
School of Pharmacy, Tokyo University of Pharmacy and Life Science, Hachioji, Japan.
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|
pubmed:publicationType |
Journal Article
|
