10466972

Source:http://linkedlifedata.com/resource/pubmed/id/10466972

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0006755, umls-concept:C0015219, umls-concept:C0017428, umls-concept:C0035647, umls-concept:C0085377, umls-concept:C0322844
pubmed:issue	3
pubmed:dateCreated	1999-9-15
pubmed:abstractText	Aedes albopictus was introduced into the United States in used tires in 1985. Its successful colonization of the upper Midwest has potential to alter the current epidemiology of bunyaviruses that circulate in the region. It is permissive for the replication of several arboviruses, including La Crosse (LACV) and Jamestown Canyon (JCV) bunyaviruses. In this study, we demonstrate the ability of LACV and JCV to coinfect Ae. albopictus mosquitoes and to form all six possible reassortant genotypes. All reassortant viruses infect Ae. albopictus orally and can be transmitted to suckling mice. All reassortants are neurovirulent in mice. However, reassortant viruses carrying the LACV M segment in the foreign genetic background of JCV are more neuroinvasive than JCV, or any other reassortant genotype. In addition, these reassortants can replicate in gerbils and infect Ae. triseriatus, characteristics of LACV, but not JCV. Because Ae. albopictus is spreading into new geographic areas and feeds on a variety of mammals, including humans, it has the potential to transmit new, emerging bunyaviruses in nature.
pubmed:grant	http://linkedlifedata.com/resource/pubmed/grant/AI-36376-02
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/0370507
pubmed:citationSubset	AIM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/Antigens, Viral, http://linkedlifedata.com/resource/pubmed/chemical/DNA Probes, http://linkedlifedata.com/resource/pubmed/chemical/RNA, Viral
pubmed:status	MEDLINE
pubmed:month	Mar
pubmed:issn	0002-9637
pubmed:author	pubmed-author:ChengL LLL, pubmed-author:ChristensenB MBM, pubmed-author:IsraelB ABA, pubmed-author:RodasJ DJD, pubmed-author:SchultzK TKT, pubmed-author:YuillT MTM
pubmed:issnType	Print
pubmed:volume	60
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	430-8
pubmed:dateRevised	2007-11-14
pubmed:meshHeading	pubmed-meshheading:10466972-Aedes, pubmed-meshheading:10466972-Animals, pubmed-meshheading:10466972-Animals, Suckling, pubmed-meshheading:10466972-Antigens, Viral, pubmed-meshheading:10466972-Blotting, Northern, pubmed-meshheading:10466972-Bunyaviridae, pubmed-meshheading:10466972-Bunyaviridae Infections, pubmed-meshheading:10466972-Cercopithecus aethiops, pubmed-meshheading:10466972-Cytopathogenic Effect, Viral, pubmed-meshheading:10466972-DNA Probes, pubmed-meshheading:10466972-Fluorescent Antibody Technique, Indirect, pubmed-meshheading:10466972-Gerbillinae, pubmed-meshheading:10466972-Insect Vectors, pubmed-meshheading:10466972-Mice, pubmed-meshheading:10466972-Neutralization Tests, pubmed-meshheading:10466972-Nucleic Acid Hybridization, pubmed-meshheading:10466972-Plasmids, pubmed-meshheading:10466972-RNA, Viral, pubmed-meshheading:10466972-Radioimmunoprecipitation Assay, pubmed-meshheading:10466972-Reassortant Viruses, pubmed-meshheading:10466972-Vero Cells, pubmed-meshheading:10466972-Viremia
pubmed:year	1999
pubmed:articleTitle	Potential for evolution of California serogroup bunyaviruses by genome reassortment in Aedes albopictus.
pubmed:affiliation	Department of Pathobiological Sciences, School of Veterinary Medicine, University of Wisconsin-Madison, 53706, USA.
pubmed:publicationType	Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, Non-U.S. Gov't