| pubmed-article:10465554 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:10465554 | lifeskim:mentions | umls-concept:C0022023 | lld:lifeskim |
| pubmed-article:10465554 | lifeskim:mentions | umls-concept:C0030956 | lld:lifeskim |
| pubmed-article:10465554 | lifeskim:mentions | umls-concept:C1167622 | lld:lifeskim |
| pubmed-article:10465554 | lifeskim:mentions | umls-concept:C0016315 | lld:lifeskim |
| pubmed-article:10465554 | lifeskim:mentions | umls-concept:C2603343 | lld:lifeskim |
| pubmed-article:10465554 | lifeskim:mentions | umls-concept:C1177210 | lld:lifeskim |
| pubmed-article:10465554 | lifeskim:mentions | umls-concept:C2346521 | lld:lifeskim |
| pubmed-article:10465554 | lifeskim:mentions | umls-concept:C0758515 | lld:lifeskim |
| pubmed-article:10465554 | lifeskim:mentions | umls-concept:C2346592 | lld:lifeskim |
| pubmed-article:10465554 | pubmed:issue | 15 | lld:pubmed |
| pubmed-article:10465554 | pubmed:dateCreated | 1999-11-24 | lld:pubmed |
| pubmed-article:10465554 | pubmed:abstractText | Binding of Zn(II), Cu(II) and Fe(II) ions to A beta1-40, A beta1-42 and a single tryptophan mutant of Abeta 1-40 in solution at pH 7.4 was studied by fluorescent titration. Job plots and fitting of titration curves revealed formation of 1:1 and 1:2 peptide-metal complexes. For dimeric peptides A beta1-40 and A betaF4W the order of metal to peptide affinities is Fe < Cu > Zn, which is in agreement with the Irving-Williams series of complex stability. The affinity of A beta1-42 for Fe increases dramatically upon aggregation: K(D) changes from ca. 100 to ca. 0.2 microM. | lld:pubmed |
| pubmed-article:10465554 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10465554 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10465554 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10465554 | pubmed:language | eng | lld:pubmed |
| pubmed-article:10465554 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10465554 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:10465554 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10465554 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10465554 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10465554 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10465554 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10465554 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10465554 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:10465554 | pubmed:month | Aug | lld:pubmed |
| pubmed-article:10465554 | pubmed:issn | 0960-894X | lld:pubmed |
| pubmed-article:10465554 | pubmed:author | pubmed-author:GlabeC GCG | lld:pubmed |
| pubmed-article:10465554 | pubmed:author | pubmed-author:YatsimirskyA... | lld:pubmed |
| pubmed-article:10465554 | pubmed:author | pubmed-author:Garzon-Rodrig... | lld:pubmed |
| pubmed-article:10465554 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:10465554 | pubmed:day | 2 | lld:pubmed |
| pubmed-article:10465554 | pubmed:volume | 9 | lld:pubmed |
| pubmed-article:10465554 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:10465554 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:10465554 | pubmed:pagination | 2243-8 | lld:pubmed |
| pubmed-article:10465554 | pubmed:dateRevised | 2010-11-18 | lld:pubmed |
| pubmed-article:10465554 | pubmed:meshHeading | pubmed-meshheading:10465554... | lld:pubmed |
| pubmed-article:10465554 | pubmed:meshHeading | pubmed-meshheading:10465554... | lld:pubmed |
| pubmed-article:10465554 | pubmed:meshHeading | pubmed-meshheading:10465554... | lld:pubmed |
| pubmed-article:10465554 | pubmed:meshHeading | pubmed-meshheading:10465554... | lld:pubmed |
| pubmed-article:10465554 | pubmed:meshHeading | pubmed-meshheading:10465554... | lld:pubmed |
| pubmed-article:10465554 | pubmed:meshHeading | pubmed-meshheading:10465554... | lld:pubmed |
| pubmed-article:10465554 | pubmed:meshHeading | pubmed-meshheading:10465554... | lld:pubmed |
| pubmed-article:10465554 | pubmed:meshHeading | pubmed-meshheading:10465554... | lld:pubmed |
| pubmed-article:10465554 | pubmed:meshHeading | pubmed-meshheading:10465554... | lld:pubmed |
| pubmed-article:10465554 | pubmed:year | 1999 | lld:pubmed |
| pubmed-article:10465554 | pubmed:articleTitle | Binding of Zn(II), Cu(II), and Fe(II) ions to Alzheimer's A beta peptide studied by fluorescence. | lld:pubmed |
| pubmed-article:10465554 | pubmed:affiliation | Department of Molecular Biology and Biochemistry, University of California at Irvine, 92697, USA. | lld:pubmed |
| pubmed-article:10465554 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:10465554 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:10465554 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10465554 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10465554 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:10465554 | lld:pubmed |
