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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
1999-9-16
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pubmed:abstractText |
Reduced activity of ferrochelatase in erythropoietic protoporphyria (EPP) results in protoporphyrin (PP) accumulation in erythrocytes and liver. Liver disease may occur in patients with EPP, some of whom develop progressive liver failure that necessitates transplantation. We investigated the mechanisms underlying EPP-associated liver disease in a mouse model of EPP.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0016-5085
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pubmed:author |
pubmed-author:BloksVV,
pubmed-author:HavingaRR,
pubmed-author:JansenP LPL,
pubmed-author:KoopenN RNR,
pubmed-author:KramerWW,
pubmed-author:KuipersFF,
pubmed-author:MüllerMM,
pubmed-author:MeermanLL,
pubmed-author:StengelinSS,
pubmed-author:Van GoorHH,
pubmed-author:WolthersB GBG
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pubmed:issnType |
Print
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pubmed:volume |
117
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
696-705
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:10464147-Animals,
pubmed-meshheading:10464147-Bile,
pubmed-meshheading:10464147-Bile Acids and Salts,
pubmed-meshheading:10464147-Biliary Tract,
pubmed-meshheading:10464147-Blotting, Northern,
pubmed-meshheading:10464147-Blotting, Western,
pubmed-meshheading:10464147-Disease Models, Animal,
pubmed-meshheading:10464147-Female,
pubmed-meshheading:10464147-Ferrochelatase,
pubmed-meshheading:10464147-Fibrosis,
pubmed-meshheading:10464147-Griseofulvin,
pubmed-meshheading:10464147-Immunohistochemistry,
pubmed-meshheading:10464147-Lipid Peroxidation,
pubmed-meshheading:10464147-Liver,
pubmed-meshheading:10464147-Male,
pubmed-meshheading:10464147-Mice,
pubmed-meshheading:10464147-Mice, Inbred BALB C,
pubmed-meshheading:10464147-Porphyria, Hepatoerythropoietic,
pubmed-meshheading:10464147-Protoporphyria, Erythropoietic
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pubmed:year |
1999
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pubmed:articleTitle |
Biliary fibrosis associated with altered bile composition in a mouse model of erythropoietic protoporphyria.
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pubmed:affiliation |
Center for Liver, Digestive, and Metabolic Diseases, Groningen Institute for Drug Studies, Groningen, The Netherlands.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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