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pubmed-article:10464131pubmed:abstractTextNitric oxide (NO)-releasing derivatives of cyclooxygenase inhibitors exhibit enhanced anti-inflammatory activity and greatly reduced gastrointestinal toxicity. We evaluated whether a similar derivatization of mesalamine (5-aminosalicylic acid) would improve its anti-inflammatory activity.lld:pubmed
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pubmed-article:10464131pubmed:articleTitleEnhanced anti-inflammatory effects of a nitric oxide-releasing derivative of mesalamine in rats.lld:pubmed
pubmed-article:10464131pubmed:affiliationDepartment of Pharmacology and Therapeutics, University of Calgary, Calgary, Alberta, Canada. wallacej@ucalgary.calld:pubmed
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