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PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
1999-11-8
pubmed:abstractText
Ten Staphylococcus caprae strains isolated from four patients and responsible for bone infections following implantation of orthopaedic material were compared to four S. caprae strains collected from milk samples of healthy goats. The following characteristics were investigated: Smal patterns, hybridization patterns with pBA2 (ribotypes), slime production, adhesion to matrix proteins (fibrinogen, fibronectin, collagen) and the staphylococcal adhesion genes (fnbA, clfA, cna, atlE, ica, fbe). None of the characteristics enabled us to distinguish the human strains from the goat strains. Slime was occasionally produced by S. caprae strains but all of them carried nucleotide sequences hybridizing at low stringency with the following genes: atlE encoding a S. epidermidis autolysin binding vitronectin and responsible for the primary adhesion to polystyrene, ica operon involved in the biosynthesis of a S. epidermidis extracellular polysaccharide, and the part of clfA encoding the serine-aspartate repeated region of a S. aureus cell-wall fibrinogen-binding protein.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
1350-0872
pubmed:author
pubmed:issnType
Print
pubmed:volume
145 ( Pt 8)
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
2033-42
pubmed:dateRevised
2008-8-29
pubmed:meshHeading
pubmed-meshheading:10463169-Animals, pubmed-meshheading:10463169-Arthroplasty, Replacement, pubmed-meshheading:10463169-Bacterial Adhesion, pubmed-meshheading:10463169-Bacterial Proteins, pubmed-meshheading:10463169-Bone Diseases, Infectious, pubmed-meshheading:10463169-Deoxyribonucleases, Type II Site-Specific, pubmed-meshheading:10463169-Electrophoresis, Gel, Pulsed-Field, pubmed-meshheading:10463169-Extracellular Matrix Proteins, pubmed-meshheading:10463169-Genes, Bacterial, pubmed-meshheading:10463169-Goats, pubmed-meshheading:10463169-Humans, pubmed-meshheading:10463169-Milk, pubmed-meshheading:10463169-Polystyrenes, pubmed-meshheading:10463169-Prosthesis-Related Infections, pubmed-meshheading:10463169-Sequence Analysis, DNA, pubmed-meshheading:10463169-Staphylococcal Infections, pubmed-meshheading:10463169-Staphylococcus
pubmed:year
1999
pubmed:articleTitle
Tracking adhesion factors in Staphylococcus caprae strains responsible for human bone infections following implantation of orthopaedic material.
pubmed:affiliation
Unité des Staphylocoques, National Reference Center for Staphylococci Institut Pasteur, Paris, France.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't