| pubmed-article:10462639 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:10462639 | lifeskim:mentions | umls-concept:C0030705 | lld:lifeskim |
| pubmed-article:10462639 | lifeskim:mentions | umls-concept:C0004610 | lld:lifeskim |
| pubmed-article:10462639 | lifeskim:mentions | umls-concept:C0021708 | lld:lifeskim |
| pubmed-article:10462639 | lifeskim:mentions | umls-concept:C0020028 | lld:lifeskim |
| pubmed-article:10462639 | lifeskim:mentions | umls-concept:C0936012 | lld:lifeskim |
| pubmed-article:10462639 | lifeskim:mentions | umls-concept:C0022804 | lld:lifeskim |
| pubmed-article:10462639 | pubmed:issue | 1 | lld:pubmed |
| pubmed-article:10462639 | pubmed:dateCreated | 1999-11-10 | lld:pubmed |
| pubmed-article:10462639 | pubmed:abstractText | An analysis of hospital-acquired bacteraemia among ICU patients was carried out over a two-year period in order to determine the incidence, associated mortality rate and susceptibility pattern of causative pathogens. There was a high incidence of bacteraemia, occurring in 127 (18.4%) of 692 patients. Mortality attributable to nosocomial bacteraemia was 52% of the total 79 deaths from all causes. The highest mortality rate (58.5%) occurred in patients with fungal infections, whilst death from Gram-negative bacteraemia was only 17%. Over 98% of patients had underlying disease. Nearly half (46.8%) of 267 organisms isolated were Gram-positive. In comparison, Gram-negative bacteria accounted for 36.6% and the rest (17.6%) were fungi (mainly Candida albicans). The majority of the bactereamic episodes were monomicrobial (90.2%). Coagulase-negative staphylococci (CNS) were the commonest pathogens isolated, representing 32.6% of all organisms. Inducible beta-lactamase producing organism (Enterobacter spp. 9.7%, Serratia marcescens 6.7%, Klebsiella pneumoniae 6% and Pseudomonas aeruginosa 6%) formed the bulk of Gram-negative bacteria. In contrast, Escherichia coli (7.5%) and K. pneumoniae (4%) were the commonest Gram-negative bacteria from hospital-acquired bacteraemia in the general hospital population. The majority (80%) of CNS were resistant to methicillin (MRSE) but susceptible to vancomycin; they were relatively resistant to erythromycin, clindamycin and beta-lactams antibiotics. Whilst Gram-negative organisms were relatively susceptible to imipenem (85%), ciprofloxacin (88%) and amikacin (87%), they had unacceptably low levels of susceptibility to cefuroxime (59.3%), cefotaxime (71%), ceftazidime (60.9%), and piperacillin (51.1%). This study shows that hospital-acquired bacteraemia in ICU patients carries a poor prognosis. Information regarding the infective agents and their susceptibility in the ICU setting is valuable for the selection of empirical therapy before culture and susceptibility results are known. | lld:pubmed |
| pubmed-article:10462639 | pubmed:language | eng | lld:pubmed |
| pubmed-article:10462639 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10462639 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:10462639 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10462639 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:10462639 | pubmed:month | Sep | lld:pubmed |
| pubmed-article:10462639 | pubmed:issn | 0195-6701 | lld:pubmed |
| pubmed-article:10462639 | pubmed:author | pubmed-author:RotimiV OVO | lld:pubmed |
| pubmed-article:10462639 | pubmed:author | pubmed-author:ChughT DTD | lld:pubmed |
| pubmed-article:10462639 | pubmed:author | pubmed-author:JamalW YWY | lld:pubmed |
| pubmed-article:10462639 | pubmed:author | pubmed-author:El-DinKK | lld:pubmed |
| pubmed-article:10462639 | pubmed:copyrightInfo | Copyright 1999 The Hospital Infection Society. | lld:pubmed |
| pubmed-article:10462639 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:10462639 | pubmed:volume | 43 | lld:pubmed |
| pubmed-article:10462639 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:10462639 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:10462639 | pubmed:pagination | 49-56 | lld:pubmed |
| pubmed-article:10462639 | pubmed:dateRevised | 2004-11-17 | lld:pubmed |
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| pubmed-article:10462639 | pubmed:year | 1999 | lld:pubmed |
| pubmed-article:10462639 | pubmed:articleTitle | An analysis of hospital-acquired bacteraemia in intensive care unit patients in a university hospital in Kuwait. | lld:pubmed |
| pubmed-article:10462639 | pubmed:affiliation | Department of Microbiology, Department of Anesthesiology, Mubarak Al-Kabeer Hospital and Faculty of Medicine, P. O. Box 24923, Safat, 13110, Kuwait. | lld:pubmed |
| pubmed-article:10462639 | pubmed:publicationType | Journal Article | lld:pubmed |
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