Source:http://linkedlifedata.com/resource/pubmed/id/10462100
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
1999-10-13
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pubmed:abstractText |
Using immunohistochemistry we studied the presence of calbindin in myenteric neurones of the guinea-pig stomach. A rabbit anti recombinant rat calbindin-D28k (CALB) stained 12, 12 and 25% of all myenteric neurones in the fundus, corpus and antrum, respectively. A rabbit anti recombinant human CALB stained 4, 4 and 16%, respectively. A mouse monoclonal antibody against the chicken intestinal CALB showed no labelling. In all regions most calbindin neurones were additionally choline acetyltransferase (ChAT) positive while only a small proportion exhibited nicotinamide adenosine dinucleatide phosphate (NADPH)-diaphorase-activity. Numerous calbindin-positive varicose nerve fibres were present within myenteric ganglia, rarely detectable in the muscle layers and virtually absent in the mucosa. This study demonstrated that a supopulation of cholinergic myenteric neurones in the stomach contain calbindin and suggested that many of these neurones fulfil interneuronal tasks.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Calcium-Binding Protein, Vitamin...,
http://linkedlifedata.com/resource/pubmed/chemical/Choline O-Acetyltransferase,
http://linkedlifedata.com/resource/pubmed/chemical/NADPH Dehydrogenase,
http://linkedlifedata.com/resource/pubmed/chemical/calbindin
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0304-3940
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
30
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pubmed:volume |
270
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
71-4
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:10462100-Animals,
pubmed-meshheading:10462100-Calcium-Binding Protein, Vitamin D-Dependent,
pubmed-meshheading:10462100-Chickens,
pubmed-meshheading:10462100-Choline O-Acetyltransferase,
pubmed-meshheading:10462100-Female,
pubmed-meshheading:10462100-Guinea Pigs,
pubmed-meshheading:10462100-Humans,
pubmed-meshheading:10462100-Immunohistochemistry,
pubmed-meshheading:10462100-Male,
pubmed-meshheading:10462100-Myenteric Plexus,
pubmed-meshheading:10462100-NADPH Dehydrogenase,
pubmed-meshheading:10462100-Nerve Fibers,
pubmed-meshheading:10462100-Neurons,
pubmed-meshheading:10462100-Rats,
pubmed-meshheading:10462100-Stomach
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pubmed:year |
1999
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pubmed:articleTitle |
Immunohistochemical evidence for the presence of calbindin containing neurones in the myenteric plexus of the guinea-pig stomach.
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pubmed:affiliation |
Department of Physiology, School of Veterinary Medicine, Hannover, Germany.
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pubmed:publicationType |
Journal Article
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