Source:http://linkedlifedata.com/resource/pubmed/id/10461090
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
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pubmed:dateCreated |
1999-10-14
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pubmed:abstractText |
Although alpha(1)-antitrypsin (AAT) deficiency is one of the most common hereditary diseases and a recognized cause of emphysema in Caucasians, variants of this deficiency are extremely rare among Orientals. We present here a Japanese emphysema patient with the AAT deficiency variant originally identified as S(iiyama). After an 8-year follow-up period, the patient suffered from repeated pulmonary Pseudomonas aeruginosa infection for 4 years. He died suddenly of massive pulmonary hemorrhage. The pathologic examination revealed a necrotic hematoma in the right S10 lobe, which exhibited pneumonia due to cytomegalovirus (CMV) infection. Pulmonary hemorrhage due to CMV can occur and be fatal in patients with emphysema and AAT deficiency.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:issn |
0025-7931
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
66
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
373-6
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pubmed:dateRevised |
2009-11-11
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pubmed:meshHeading |
pubmed-meshheading:10461090-Adult,
pubmed-meshheading:10461090-Cytomegalovirus Infections,
pubmed-meshheading:10461090-Hemorrhage,
pubmed-meshheading:10461090-Humans,
pubmed-meshheading:10461090-Lung Diseases,
pubmed-meshheading:10461090-Male,
pubmed-meshheading:10461090-Pneumonia, Viral,
pubmed-meshheading:10461090-Pulmonary Emphysema,
pubmed-meshheading:10461090-alpha 1-Antitrypsin Deficiency
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pubmed:year |
1999
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pubmed:articleTitle |
Massive pulmonary hemorrhage due to cytomegalovirus infection in a Japanese patient with alpha-1-antitrypsin-deficient emphysema.
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pubmed:affiliation |
Department of Internal Medicine, Nagano Red Cross Hospital, Nagano, Japan.
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pubmed:publicationType |
Journal Article,
Case Reports
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