Source:http://linkedlifedata.com/resource/pubmed/id/10459684
Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
|
pubmed:dateCreated |
1999-10-20
|
pubmed:abstractText |
Ten healthy men (mean age, 33.9 years) participated in two experimental sessions cross-overed randomly in a double-blind manner: one with the placebo and another with 0.125 mg of triazolam (TRZ). Resting electroencephalography and event-related potential under oddball paradigm were recorded before the drug administration, and 1, 2, 4, 6 and 8 h after that. P300 waveforms were analyzed by peak amplitudes and 30-ms bin data. Triazolam may cause cognitive dysfunction without general sedation or apparent sleepiness, and this effect appeared 2 h, 4 h and 6 h, most prominently 6 h, after TRZ administration.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Apr
|
pubmed:issn |
1323-1316
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
53
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
185-7
|
pubmed:dateRevised |
2004-11-17
|
pubmed:meshHeading |
pubmed-meshheading:10459684-Adult,
pubmed-meshheading:10459684-Arousal,
pubmed-meshheading:10459684-Attention,
pubmed-meshheading:10459684-Cognition,
pubmed-meshheading:10459684-Cross-Over Studies,
pubmed-meshheading:10459684-Dose-Response Relationship, Drug,
pubmed-meshheading:10459684-Double-Blind Method,
pubmed-meshheading:10459684-Electroencephalography,
pubmed-meshheading:10459684-Event-Related Potentials, P300,
pubmed-meshheading:10459684-Humans,
pubmed-meshheading:10459684-Hypnotics and Sedatives,
pubmed-meshheading:10459684-Male,
pubmed-meshheading:10459684-Triazolam
|
pubmed:year |
1999
|
pubmed:articleTitle |
Effects of a small dose of triazolam on P300.
|
pubmed:affiliation |
Department of Psychiatry, Kohnodai Hospital, National Center of Neurology and Psychiatry, Ichikawa, Chiba, Japan.
|
pubmed:publicationType |
Journal Article,
Clinical Trial,
Randomized Controlled Trial
|