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10456492
Source:
http://linkedlifedata.com/resource/pubmed/id/10456492
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Predicate
Object
rdf:type
pubmed:Citation
lifeskim:mentions
umls-concept:C0005508
,
umls-concept:C0052429
,
umls-concept:C0442805
,
umls-concept:C0452456
pubmed:issue
5
pubmed:dateCreated
1999-10-21
pubmed:abstractText
To evaluate the effect of grapefruit juice on the pharmacokinetics of artemether in plasma and saliva after a single oral dose and to detect concentration-dependent electrocardiographic changes (bradycardia and QTc prolongation).
pubmed:language
eng
pubmed:journal
http://linkedlifedata.com/resource/pubmed/journal/1256165
pubmed:citationSubset
IM
pubmed:chemical
http://linkedlifedata.com/resource/pubmed/chemical/Antimalarials
,
http://linkedlifedata.com/resource/pubmed/chemical/Artemisinins
,
http://linkedlifedata.com/resource/pubmed/chemical/Sesquiterpenes
,
http://linkedlifedata.com/resource/pubmed/chemical/artemether
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
0031-6970
pubmed:author
pubmed-author:GupteJJ
,
pubmed-author:RuttenJ PJP
,
pubmed-author:van AgtmaelM AMA
,
pubmed-author:van BoxtelC JCJ
,
pubmed-author:van der WöstenT HTH
pubmed:issnType
Print
pubmed:volume
55
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
405-10
pubmed:dateRevised
2009-8-18
pubmed:meshHeading
pubmed-meshheading:10456492-Adult
,
pubmed-meshheading:10456492-Antimalarials
,
pubmed-meshheading:10456492-Artemisinins
,
pubmed-meshheading:10456492-Biological Availability
,
pubmed-meshheading:10456492-Chromatography, High Pressure Liquid
,
pubmed-meshheading:10456492-Citrus
,
pubmed-meshheading:10456492-Drug Interactions
,
pubmed-meshheading:10456492-Electrocardiography
,
pubmed-meshheading:10456492-Heart
,
pubmed-meshheading:10456492-Humans
,
pubmed-meshheading:10456492-Male
,
pubmed-meshheading:10456492-Saliva
,
pubmed-meshheading:10456492-Sesquiterpenes
pubmed:year
1999
pubmed:articleTitle
Grapefruit juice increases the bioavailability of artemether.
pubmed:affiliation
Department of Clinical Pharmacology and Pharmacotherapy, Amsterdam, The Netherlands.
pubmed:publicationType
Journal Article