Linked Life Data

10456207

Source:http://linkedlifedata.com/resource/pubmed/id/10456207

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PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
1999-9-22
pubmed:abstractText
Ten type 1 diabetic patients recorded their daily home blood glucose values, pre- and post-prandially, for 12 weeks. Blood was collected weekly for HbA1c and total haemoglobin measurement. A rolling 28-day mean of all blood glucose values and a glycation index (the ratio of the HbA1c to the rolling mean blood glucose) were calculated. In the pooled patients' data, there was a large scatter of results about the HbA1c versus mean blood glucose regression line. There was less variation in the results of individual patients. The glycation indices showed marked inter-individual variation, and in 60% of patients there was an inverse relationship between glycation index and mean blood glucose, suggesting a non-linear relationship between mean blood glucose and HbA1c. Patients should be monitored on the basis of their own previous results, and in some patients blood HbA1c may be a less sensitive index of mean blood glucose concentration at higher glucose levels.
pubmed:commentsCorrections
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
0004-5632
pubmed:author
pubmed:issnType
Print
pubmed:volume
36 ( Pt 4)
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
451-9
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1999
pubmed:articleTitle
Differences in rates of glycation (glycation index) may significantly affect individual HbA1c results in type 1 diabetes.
pubmed:affiliation
Department of Medical Biochemistry, Wrexham Maelor Hospital, UK. peter.hudson@new-tr.wales.nhs.uk
pubmed:publicationType
Journal Article