10450981

Source:http://linkedlifedata.com/resource/pubmed/id/10450981

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0034325, umls-concept:C0082341, umls-concept:C0205314, umls-concept:C0231491, umls-concept:C0243072, umls-concept:C0679622
pubmed:issue	14
pubmed:dateCreated	1999-9-24
pubmed:abstractText	A new series of benzopyrano[3,4-c]pyrrole derivatives were synthesized and evaluated for their interaction with dopamine D3 versus D2 receptors. Amongst these compounds, 4x (S 33084) was found to be a potent and selective dopamine D3 receptor antagonist.
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/9107377
pubmed:citationSubset	IM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/5-hydroxy-2-N,N-dipropylaminotetrali..., http://linkedlifedata.com/resource/pubmed/chemical/7-hydroxy-2-N,N-dipropylaminotetrali..., http://linkedlifedata.com/resource/pubmed/chemical/8-Hydroxy-2-(di-n-propylamino)tetral..., http://linkedlifedata.com/resource/pubmed/chemical/Benzopyrans, http://linkedlifedata.com/resource/pubmed/chemical/DRD3 protein, human, http://linkedlifedata.com/resource/pubmed/chemical/Dopamine Agonists, http://linkedlifedata.com/resource/pubmed/chemical/Dopamine Antagonists, http://linkedlifedata.com/resource/pubmed/chemical/Guanosine 5'-O-(3-Thiotriphosphate), http://linkedlifedata.com/resource/pubmed/chemical/Iodine Radioisotopes, http://linkedlifedata.com/resource/pubmed/chemical/Pyrroles, http://linkedlifedata.com/resource/pubmed/chemical/Pyrrolidines, http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Dopamine D2, http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Dopamine D3, http://linkedlifedata.com/resource/pubmed/chemical/Sulpiride, http://linkedlifedata.com/resource/pubmed/chemical/Tetrahydronaphthalenes
pubmed:status	MEDLINE
pubmed:month	Jul
pubmed:issn	0960-894X
pubmed:author	pubmed-author:AudinotVV, pubmed-author:CussacDD, pubmed-author:DubuffetTT, pubmed-author:LavielleGG, pubmed-author:LoutzAA, pubmed-author:MillanM JMJ, pubmed-author:Newman-TancrediAA
pubmed:issnType	Print
pubmed:day	19
pubmed:volume	9
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	2059-64
pubmed:dateRevised	2005-11-17
pubmed:meshHeading	pubmed-meshheading:10450981-8-Hydroxy-2-(di-n-propylamino)tetralin, pubmed-meshheading:10450981-Animals, pubmed-meshheading:10450981-Benzopyrans, pubmed-meshheading:10450981-CHO Cells, pubmed-meshheading:10450981-Cricetinae, pubmed-meshheading:10450981-Dopamine Agonists, pubmed-meshheading:10450981-Dopamine Antagonists, pubmed-meshheading:10450981-Guanosine 5'-O-(3-Thiotriphosphate), pubmed-meshheading:10450981-Humans, pubmed-meshheading:10450981-Iodine Radioisotopes, pubmed-meshheading:10450981-Pyrroles, pubmed-meshheading:10450981-Pyrrolidines, pubmed-meshheading:10450981-Receptors, Dopamine D2, pubmed-meshheading:10450981-Receptors, Dopamine D3, pubmed-meshheading:10450981-Structure-Activity Relationship, pubmed-meshheading:10450981-Sulpiride, pubmed-meshheading:10450981-Tetrahydronaphthalenes, pubmed-meshheading:10450981-Transfection
pubmed:year	1999
pubmed:articleTitle	Novel benzopyrano[3,4-c]pyrrole derivatives as potent and selective dopamine D3 receptor antagonist.
pubmed:affiliation	Institut de Recherches Servier, Centre de Recherches de Croissy, Croissy sur Seine, France.
pubmed:publicationType	Journal Article