Source:http://linkedlifedata.com/resource/pubmed/id/10450532
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
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pubmed:dateCreated |
1999-10-5
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pubmed:abstractText |
The urinary metabolic pattern after administration of the radiolabeled non-provitamin A carotenoid canthaxanthin was investigated in rats. In the rather complex HPLC urinary metabolic pattern a fraction was found which was conjugated. Deconjugation of the polar conjugates with glusulase, purification of the metabolite with HPLC and identification with GC-MS and NMR revealed that it was 3-hydroxy-4-oxo-7,8-dihydro-beta-ionone. This structure was confirmed by comparisons with HPLC retention times, UV/VIS- and NMR-spectroscopy and GC-MS of the synthesized compound.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0300-9831
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
69
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
268-72
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pubmed:dateRevised |
2007-2-21
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pubmed:meshHeading |
pubmed-meshheading:10450532-Animals,
pubmed-meshheading:10450532-Canthaxanthin,
pubmed-meshheading:10450532-Chromatography, High Pressure Liquid,
pubmed-meshheading:10450532-Food Coloring Agents,
pubmed-meshheading:10450532-Gas Chromatography-Mass Spectrometry,
pubmed-meshheading:10450532-Magnetic Resonance Spectroscopy,
pubmed-meshheading:10450532-Male,
pubmed-meshheading:10450532-Rats,
pubmed-meshheading:10450532-Rats, Wistar
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pubmed:year |
1999
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pubmed:articleTitle |
Isolation and identification of a major urinary canthaxanthin metabolite in rats.
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pubmed:affiliation |
F. Hoffmann-La Roche Ltd., Basel, Switzerland.
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pubmed:publicationType |
Journal Article
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