Source:http://linkedlifedata.com/resource/pubmed/id/10450420
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:dateCreated |
1999-8-31
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pubmed:abstractText |
Plasmodium falciparum parasites exist as genetically distinct haploid clones in infected people. In the Kilombero valley in south-east Tanzania, at least 85% of the inhabitants of Michenga village harbour more than one clone. Using 2 highly polymorphic unlinked markers, it has been estimated that each infected person harbours between one and 6 P. falciparum clones at any one time, with a mean of 3.5 clones. When mosquitoes acquire gametocytes of 2 different clones in a blood meal, crossing generates recombinant clones differing from their parental genotypes. The inbreeding coefficient of the parasite population has been estimated as 0.33.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0035-9203
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
93 Suppl 1
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
11-4
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:10450420-Animals,
pubmed-meshheading:10450420-Anopheles,
pubmed-meshheading:10450420-Antigens, Protozoan,
pubmed-meshheading:10450420-Clone Cells,
pubmed-meshheading:10450420-Genetic Markers,
pubmed-meshheading:10450420-Humans,
pubmed-meshheading:10450420-Malaria, Falciparum,
pubmed-meshheading:10450420-Plasmodium falciparum,
pubmed-meshheading:10450420-Polymerase Chain Reaction,
pubmed-meshheading:10450420-Protozoan Proteins,
pubmed-meshheading:10450420-Reproduction,
pubmed-meshheading:10450420-Tanzania
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pubmed:year |
1999
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pubmed:articleTitle |
Genetic structure and dynamics of Plasmodium falciparum infections in the Kilombero region of Tanzania.
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pubmed:affiliation |
Institute of Cell, Animal and Population Biology, University of Edinburgh, Scotland, UK. h.babiker@ed.ac.uk
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pubmed:publicationType |
Journal Article,
Review,
Research Support, Non-U.S. Gov't
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