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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
7
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pubmed:dateCreated |
1999-9-30
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pubmed:abstractText |
The recognition of phosphorylated nonpeptidic microbial metabolites by Vgamma9Vdelta2 T cells does not appear to require the presence of MHC molecules or antigen processing, permitting rapid responses against microbial pathogens. These may constitute an important area of natural anti-infectious immunity. To provide evidence of their involvement in immune reactivities against mycobacteria, we measured the responsiveness of peripheral blood Vgamma9Vdelta2 T cells in children with primary Mycobacterium tuberculosis (MTB) infections.
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pubmed:grant |
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/10449808-1827825,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10449808-1978758,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10449808-2185330,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10449808-2443566,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10449808-3102967,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10449808-4210333,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10449808-6216412,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10449808-7589086,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10449808-7621879,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10449808-7751641,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10449808-7753173,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10449808-8146660,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10449808-8892660,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10449808-9132281,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10449808-9362537,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10449808-9378958,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10449808-9394804,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10449808-9550399,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10449808-9639988,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10449808-9670986
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Antigens,
http://linkedlifedata.com/resource/pubmed/chemical/Antigens, Bacterial,
http://linkedlifedata.com/resource/pubmed/chemical/Diphosphates,
http://linkedlifedata.com/resource/pubmed/chemical/Hemiterpenes,
http://linkedlifedata.com/resource/pubmed/chemical/Interferon-gamma,
http://linkedlifedata.com/resource/pubmed/chemical/Ligands,
http://linkedlifedata.com/resource/pubmed/chemical/Organophosphorus Compounds,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Antigen, T-Cell...,
http://linkedlifedata.com/resource/pubmed/chemical/Sugar Phosphates,
http://linkedlifedata.com/resource/pubmed/chemical/Tumor Necrosis Factor-alpha,
http://linkedlifedata.com/resource/pubmed/chemical/isopentenyl pyrophosphate
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
1076-1551
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
5
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
471-6
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
pubmed-meshheading:10449808-Animals,
pubmed-meshheading:10449808-Antigens,
pubmed-meshheading:10449808-Antigens, Bacterial,
pubmed-meshheading:10449808-Case-Control Studies,
pubmed-meshheading:10449808-Child,
pubmed-meshheading:10449808-Child, Preschool,
pubmed-meshheading:10449808-Diphosphates,
pubmed-meshheading:10449808-Female,
pubmed-meshheading:10449808-Hemiterpenes,
pubmed-meshheading:10449808-Humans,
pubmed-meshheading:10449808-Infant,
pubmed-meshheading:10449808-Interferon-gamma,
pubmed-meshheading:10449808-Ligands,
pubmed-meshheading:10449808-Macaca mulatta,
pubmed-meshheading:10449808-Male,
pubmed-meshheading:10449808-Mycobacterium tuberculosis,
pubmed-meshheading:10449808-Organophosphorus Compounds,
pubmed-meshheading:10449808-Receptors, Antigen, T-Cell, gamma-delta,
pubmed-meshheading:10449808-Sugar Phosphates,
pubmed-meshheading:10449808-T-Lymphocytes,
pubmed-meshheading:10449808-Tuberculosis,
pubmed-meshheading:10449808-Tumor Necrosis Factor-alpha
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pubmed:year |
1999
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pubmed:articleTitle |
In vivo gammadelta T cell priming to mycobacterial antigens by primary Mycobacterium tuberculosis infection and exposure to nonpeptidic ligands.
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pubmed:affiliation |
Department of Medical Microbiology and Immunology, University of Wisconsin Medical School, University of Wisconsin Comprehensive Cancer Center, and Wisconsin Regional Primate Research Center, Madison, Wisconsin 53706, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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