Source:http://linkedlifedata.com/resource/pubmed/id/10445070
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
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pubmed:dateCreated |
1999-9-20
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pubmed:abstractText |
This study correlates static and flow-cytometric analysis on paraffin-embedded and fresh material of salivary gland carcinomas. Nuclear suspensions for DNA analysis were prepared from paraffin-embedded and fresh material. Comparison of the results of static and flow cytometry on paraffin-embedded material revealed no significant correlation between DNA ploidy and S-phase value. The coefficients of variation were significantly lower for static than for flow cytometry (p < 0.05). Flow-cytometric analysis on fresh and paraffin-embedded material correlated well concerning DNA ploidy, but not for the S-phase. The coefficients of variation were significantly lower for the fresh than for the paraffin-embedded material (p < 0.001). Cytometric analysis on paraffin-embedded material of malignant salivary gland carcinomas should be critically evaluated. There is a need for flow-cytometric investigations on fresh material to clarify further the prognostic value of this method.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0001-6489
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
119
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
510-5
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:10445070-DNA, Neoplasm,
pubmed-meshheading:10445070-Flow Cytometry,
pubmed-meshheading:10445070-Humans,
pubmed-meshheading:10445070-Paraffin Embedding,
pubmed-meshheading:10445070-Ploidies,
pubmed-meshheading:10445070-S Phase,
pubmed-meshheading:10445070-Salivary Gland Neoplasms,
pubmed-meshheading:10445070-Salivary Glands
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pubmed:year |
1999
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pubmed:articleTitle |
DNA analysis of malignant salivary gland carcinomas: comparison of different tissue preparations and measuring techniques.
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pubmed:affiliation |
Department of Otolaryngology, University Hospital, University of Trondheim, Norway.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
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