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rdf:type |
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lifeskim:mentions |
umls-concept:C0027726,
umls-concept:C0030685,
umls-concept:C0030705,
umls-concept:C0078058,
umls-concept:C0123759,
umls-concept:C0205307,
umls-concept:C0254610,
umls-concept:C0391871,
umls-concept:C0442796,
umls-concept:C0680255,
umls-concept:C1280500,
umls-concept:C1283071,
umls-concept:C1963578,
umls-concept:C2243049
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pubmed:issue |
1
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pubmed:dateCreated |
1999-9-28
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pubmed:abstractText |
The vascular permeability factor (VPF) is a lymphokine that has been shown to play a role in minimal-change nephrotic syndrome (MCNS). A better understanding of the mechanisms that upregulate VPF release is of basic importance to control the immune system in nephrotic syndrome (NS). Interleukin (IL)-15 is a key inducer of differentiation of uncommitted T helper cells, which regulates cellular immunity. The cytokine IL-15 appears to mimic the stimulatory activity of IL-2 on T cells.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0301-0430
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
52
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
10-8
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:10442490-Adolescent,
pubmed-meshheading:10442490-Adult,
pubmed-meshheading:10442490-Cells, Cultured,
pubmed-meshheading:10442490-Concanavalin A,
pubmed-meshheading:10442490-Drug Synergism,
pubmed-meshheading:10442490-Endothelial Growth Factors,
pubmed-meshheading:10442490-Female,
pubmed-meshheading:10442490-Glucocorticoids,
pubmed-meshheading:10442490-Humans,
pubmed-meshheading:10442490-Interleukin-12,
pubmed-meshheading:10442490-Interleukin-15,
pubmed-meshheading:10442490-Leukocytes, Mononuclear,
pubmed-meshheading:10442490-Lymphokines,
pubmed-meshheading:10442490-Male,
pubmed-meshheading:10442490-Nephrosis, Lipoid,
pubmed-meshheading:10442490-Nephrotic Syndrome,
pubmed-meshheading:10442490-Prednisolone,
pubmed-meshheading:10442490-Protein Isoforms,
pubmed-meshheading:10442490-Reference Values,
pubmed-meshheading:10442490-Vascular Endothelial Growth Factor A,
pubmed-meshheading:10442490-Vascular Endothelial Growth Factors
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pubmed:year |
1999
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pubmed:articleTitle |
Interleukin-15 and interleukin-12 have an additive effect on the release of vascular permeability factor by peripheral blood mononuclear cells in normals and in patients with nephrotic syndrome.
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pubmed:affiliation |
Second Department of Internal Medicine, Nihon University School of Medicine, Tokyo, Japan.
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pubmed:publicationType |
Journal Article
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