Linked Life Data

10442026

Source:http://linkedlifedata.com/resource/pubmed/id/10442026

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
1999-10-21
pubmed:abstractText
To determine if the P300 component of the event-related potential indexes risk for substance use and related disorders, we presented a community sample of 377 16-18-year-old males a visual oddball task and selected 31 subjects with the smallest and 31 subjects with the largest P300 amplitudes. An additional 31 subjects whose amplitudes fell in the middle of the amplitude distribution were assigned to the average group. The small and average amplitude groups were more likely to have alcohol dependence and more symptoms of alcohol dependence than the large amplitude subjects. The small amplitude group had more symptoms of illicit drug dependence than the other groups. There was also a significantly larger proportion of subjects with externalizing disorders in the small amplitude group than in the large P300 group. These findings suggest that P300 amplitude may index a spectrum of risk for disinhibited psychopathology.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0048-5772
pubmed:author
pubmed:issnType
Print
pubmed:volume
36
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
583-90
pubmed:dateRevised
2009-11-11
pubmed:meshHeading
pubmed:year
1999
pubmed:articleTitle
Substance dependence and externalizing psychopathology in adolescent boys with small, average, or large P300 event-related potential amplitude.
pubmed:affiliation
Department of Psychology, University of Minnesota, Minneapolis 55455, USA.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Twin Study