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pubmed-article:10439467pubmed:abstractTextThe present investigation aimed to examine associations of anaemia with dementia. Analysis of community-dwelling, elderly subjects characterized for different dementias failed to confirm a previously reported association of anaemia with Alzheimer's disease (AD) but revealed instead a significant association with vascular dementia (VAD). Nearly 45% of VAD subjects were anaemic, compared with 17% of controls. Close to one-third of all subjects with haemoglobin levels > 0.5 g/dl below reference anaemia levels had VAD. Co-existing VAD may explain previous links between AD and anaemia. The association was independent of age, dementia severity and a range of other factors including vitamin B 12 and folate levels. Anaemia can exacerbate focal cerebral ischaemia and could precipitate or amplify VAD symptoms in elderly subjects with vasculopathy.lld:pubmed
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pubmed-article:10439467pubmed:dateRevised2006-11-15lld:pubmed
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pubmed-article:10439467pubmed:articleTitleEvidence for association of anaemia with vascular dementia.lld:pubmed
pubmed-article:10439467pubmed:affiliationDepartment of Medicine, University of Sydney, NSW, Australia.lld:pubmed
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