Source:http://linkedlifedata.com/resource/pubmed/id/10439467
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
11
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pubmed:dateCreated |
1999-9-30
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pubmed:abstractText |
The present investigation aimed to examine associations of anaemia with dementia. Analysis of community-dwelling, elderly subjects characterized for different dementias failed to confirm a previously reported association of anaemia with Alzheimer's disease (AD) but revealed instead a significant association with vascular dementia (VAD). Nearly 45% of VAD subjects were anaemic, compared with 17% of controls. Close to one-third of all subjects with haemoglobin levels > 0.5 g/dl below reference anaemia levels had VAD. Co-existing VAD may explain previous links between AD and anaemia. The association was independent of age, dementia severity and a range of other factors including vitamin B 12 and folate levels. Anaemia can exacerbate focal cerebral ischaemia and could precipitate or amplify VAD symptoms in elderly subjects with vasculopathy.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0959-4965
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
2
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pubmed:volume |
10
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2377-81
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:10439467-Aged,
pubmed-meshheading:10439467-Aged, 80 and over,
pubmed-meshheading:10439467-Alzheimer Disease,
pubmed-meshheading:10439467-Anemia,
pubmed-meshheading:10439467-Dementia, Vascular,
pubmed-meshheading:10439467-Female,
pubmed-meshheading:10439467-Hemoglobins,
pubmed-meshheading:10439467-Humans,
pubmed-meshheading:10439467-Male,
pubmed-meshheading:10439467-Psychiatric Status Rating Scales,
pubmed-meshheading:10439467-Retrospective Studies
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pubmed:year |
1999
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pubmed:articleTitle |
Evidence for association of anaemia with vascular dementia.
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pubmed:affiliation |
Department of Medicine, University of Sydney, NSW, Australia.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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