Linked Life Data

10435683

Source:http://linkedlifedata.com/resource/pubmed/id/10435683

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1999-9-28
pubmed:abstractText
Helicobacter pylori infection is currently treated with antimicrobial agents in combination with antacids. Recent studies have described the in vitro bactericidal activity of fish oils and polyunsaturated fatty acids on H. pylori, and reduced rates of duodenal ulcer in people with high intake of these substances. In this study we have tested the in vitro activity of three different fish oil formulations on H. pylori strains using the Kirby Bauer method and an in vitro antibacterial test on bacteria adhered to cellular monolayers. Our results demonstrate that one of the oils is active. In this study we cannot speculate on which component of the active oil is effective and its mechanism of action, but we hypothesize that a higher concentration of icosapentaenoic acid and docosahexaenoic acid occurs in the active oil. Further in vitro and in vivo studies are needed before proposing fish oils as treatment of H. pylori infection.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
1120-009X
pubmed:author
pubmed:issnType
Print
pubmed:volume
11
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
207-10
pubmed:dateRevised
2009-8-4
pubmed:meshHeading
pubmed:year
1999
pubmed:articleTitle
Effects of three different fish oil formulations on Helicobacter pylori growth and viability: in vitro study.
pubmed:affiliation
L. Sacco Teaching Hospital, University of Milan, Milano, Italy. microbio@imiucca.csi.unimi.it
pubmed:publicationType
Journal Article