Source:http://linkedlifedata.com/resource/pubmed/id/10431812
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
1999-8-26
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pubmed:abstractText |
We determined cytosolic phospholipase A2 activity of the corpus luteum during luteolysis in pregnant and post-partum rats. Phospholipase A2 activity and its metabolite prostaglandin F2alpha in the corpus luteum remarkably increased just before parturition and further rose transiently during post-partum structural luteolysis. The absence of a pups' suckling stimulus delayed corpus luteum involution, being associated with an altered fluctuation in phospholipase A2 activity and depressed prostaglandin F2alpha levels. Exogenous prolactin had a reversal effect. Pharmacological and immunochemical characterization suggests multiple isoforms of phospholipase A2 in a pregnant corpus luteum. These results show the increased phospholipase A2 activity and its possible implication in luteolysis in pregnant rats.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0014-5793
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
9
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pubmed:volume |
454
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
225-8
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:10431812-Animals,
pubmed-meshheading:10431812-Corpus Luteum,
pubmed-meshheading:10431812-Enzyme Activation,
pubmed-meshheading:10431812-Female,
pubmed-meshheading:10431812-Labor, Obstetric,
pubmed-meshheading:10431812-Phospholipases A,
pubmed-meshheading:10431812-Phospholipases A2,
pubmed-meshheading:10431812-Pregnancy,
pubmed-meshheading:10431812-Pregnancy, Animal,
pubmed-meshheading:10431812-Rats,
pubmed-meshheading:10431812-Rats, Wistar
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pubmed:year |
1999
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pubmed:articleTitle |
Luteal phospholipase A2 activity increases during functional and structural luteolysis in pregnant rats.
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pubmed:affiliation |
Laboratory of Veterinary Physiology, Kitasato University School of Veterinary Medicine and Animal Sciences, Towada, Aomori, Japan. kurusu@vmas.kitasato-u.ac.jp
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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