Source:http://linkedlifedata.com/resource/pubmed/id/10430248
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
1999-8-6
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pubmed:abstractText |
Inoperable hepatocellular carcinoma is an incurable malignancy with no accepted standard therapy. Chemotherapy has demonstrated occasional responses and the need is great for a new and effective agent. Therefore the authors conducted this Phase II trial of a novel thymidylate synthase inhibitor, nolatrexed dihydrochloride (designed using structure-based computer modeling), in patients with advanced hepatocellular carcinoma.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0008-543X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
1
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pubmed:volume |
86
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
410-4
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:10430248-Adult,
pubmed-meshheading:10430248-Aged,
pubmed-meshheading:10430248-Antimetabolites, Antineoplastic,
pubmed-meshheading:10430248-Carcinoma, Hepatocellular,
pubmed-meshheading:10430248-Female,
pubmed-meshheading:10430248-Humans,
pubmed-meshheading:10430248-Liver Neoplasms,
pubmed-meshheading:10430248-Male,
pubmed-meshheading:10430248-Middle Aged,
pubmed-meshheading:10430248-Neoplasm Staging,
pubmed-meshheading:10430248-Quinazolines,
pubmed-meshheading:10430248-Survival Analysis,
pubmed-meshheading:10430248-Thymidylate Synthase
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pubmed:year |
1999
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pubmed:articleTitle |
A Phase II trial of nolatrexed dihydrochloride in patients with advanced hepatocellular carcinoma.
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pubmed:affiliation |
Boston Center for Liver Cancer, Beth Israel Deaconess Medical Center, Harvard Medical School, Massachusetts 02215, USA.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Research Support, Non-U.S. Gov't,
Multicenter Study,
Clinical Trial, Phase II
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