Linked Life Data

10418710

Source:http://linkedlifedata.com/resource/pubmed/id/10418710

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1999-8-3
pubmed:abstractText
Cancer cases are often clustered in certain families and pedigree analysis indicates that at least 5% of cancer patients have a genetic predisposition to the disease. During the past decade the basic mechanisms for hereditary cancer have been outlined and a large number of the genes involved have been identified. This rapid development has changed the clinical management of cancer families, which now includes surveillance programs directed to early diagnosis of tumors as well as predictive mutation testing to identify gene carriers. This review outlines the molecular basis for hereditary cancer that has become the basis for genetic counseling of cancer families. The organization of clinics for cancer families in Sweden and the clinical implications of surveillance programs and gene testing for cancer predisposition are discussed.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:issn
0284-186X
pubmed:author
pubmed:issnType
Print
pubmed:volume
38
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
439-47
pubmed:dateRevised
2009-5-12
pubmed:meshHeading
pubmed:year
1999
pubmed:articleTitle
Hereditary cancer.
pubmed:affiliation
Department of Molecular Medicine, Karolinska Hospital, Stockholm, Sweden.
pubmed:publicationType
Journal Article, Review, Research Support, Non-U.S. Gov't