| pubmed-article:10418126 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:10418126 | lifeskim:mentions | umls-concept:C0014181 | lld:lifeskim |
| pubmed-article:10418126 | lifeskim:mentions | umls-concept:C0036025 | lld:lifeskim |
| pubmed-article:10418126 | lifeskim:mentions | umls-concept:C0034840 | lld:lifeskim |
| pubmed-article:10418126 | lifeskim:mentions | umls-concept:C1261322 | lld:lifeskim |
| pubmed-article:10418126 | lifeskim:mentions | umls-concept:C0920644 | lld:lifeskim |
| pubmed-article:10418126 | pubmed:issue | 1 | lld:pubmed |
| pubmed-article:10418126 | pubmed:dateCreated | 1999-8-13 | lld:pubmed |
| pubmed-article:10418126 | pubmed:abstractText | Steroid hormones are small lipophilic molecules that control a wide range of responses in both the developing and adult organism. The actions of these molecules are mediated by soluble receptor proteins that function as hormone-activated transcription factors. The first steroid receptors were expressed in the yeast Saccharomyces cerevisiae over 10 years ago, and to date virtually all the classical steroid receptors, together with a number of non-steroid members of the nuclear receptor superfamily, have been expressed in yeast. The ability to reconstitute steroid receptor signalling in yeast cells by co-expression of the receptor protein and a reporter gene driven by the appropriate hormone response element has presented researchers with a powerful model system for investigating receptor action. In this review, the use of yeast-based steroid receptor transactivation assays to investigate the roles of molecular chaperones, the mechanisms of DNA binding and gene activation, and the functional properties of hormone mimics will be discussed. | lld:pubmed |
| pubmed-article:10418126 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10418126 | pubmed:language | eng | lld:pubmed |
| pubmed-article:10418126 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10418126 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:10418126 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10418126 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10418126 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10418126 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10418126 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10418126 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10418126 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10418126 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10418126 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10418126 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10418126 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10418126 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:10418126 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:10418126 | pubmed:month | Jul | lld:pubmed |
| pubmed-article:10418126 | pubmed:issn | 0378-1097 | lld:pubmed |
| pubmed-article:10418126 | pubmed:author | pubmed-author:McEwanI JIJ | lld:pubmed |
| pubmed-article:10418126 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:10418126 | pubmed:day | 1 | lld:pubmed |
| pubmed-article:10418126 | pubmed:volume | 176 | lld:pubmed |
| pubmed-article:10418126 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:10418126 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:10418126 | pubmed:pagination | 1-9 | lld:pubmed |
| pubmed-article:10418126 | pubmed:dateRevised | 2009-5-21 | lld:pubmed |
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| pubmed-article:10418126 | pubmed:year | 1999 | lld:pubmed |
| pubmed-article:10418126 | pubmed:articleTitle | Investigation of steroid receptor function in the budding yeast Saccharomyces cerevisiae. | lld:pubmed |
| pubmed-article:10418126 | pubmed:affiliation | Department of Molecular and Cell Biology, University of Aberdeen, Foresterhill, UK. iain.mcewan@abdn.ac.uk | lld:pubmed |
| pubmed-article:10418126 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:10418126 | pubmed:publicationType | Review | lld:pubmed |
| pubmed-article:10418126 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
