Source:http://linkedlifedata.com/resource/pubmed/id/10417717
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
6
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pubmed:dateCreated |
1999-12-9
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pubmed:abstractText |
GT-1 belongs to the class of trihelix DNA-binding proteins and binds to a promoter sequence found in many different genes. Data presented in this report show that GT-1 contains a trans-activation function in yeast and in plant cells. However, in tobacco BY-2 protoplasts, this activity functions only when an internal region containing the DNA-binding domain is deleted. Gel-shift and co-immunoprecipitation assays have revealed that GT-1 can interact with and stabilize the TFIIA-TBP-TATA complex. These results suggest that GT-1 may activate transcription through direct inter- action with the transcriptional pre-initiation complex.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0960-7412
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
18
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
663-8
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:10417717-Arabidopsis,
pubmed-meshheading:10417717-DNA-Binding Proteins,
pubmed-meshheading:10417717-Nuclear Proteins,
pubmed-meshheading:10417717-Plants, Toxic,
pubmed-meshheading:10417717-Saccharomyces cerevisiae,
pubmed-meshheading:10417717-Tobacco,
pubmed-meshheading:10417717-Transcription Factors,
pubmed-meshheading:10417717-Transcriptional Activation
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pubmed:year |
1999
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pubmed:articleTitle |
Transcriptional activation by Arabidopsis GT-1 may be through interaction with TFIIA-TBP-TATA complex.
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pubmed:affiliation |
Laboratoire de Génétique Moléculaire des Plantes, Université de Picardie Jules Verne, Amiens, France.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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