Linked Life Data

10417255

Source:http://linkedlifedata.com/resource/pubmed/id/10417255

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1999-9-17
pubmed:abstractText
Diffusion tensor imaging is a magnetic resonance method which provides quantitative measurements of the directionality (anisotropy) of diffusion. Anisotropy measurements can be used to obtain quantitative information about the microstructural integrity of white matter tracts. In intact tracts diffusion is restricted and directional because water molecules move predominantly longitudinally to tracts. The aim of this study was to measure the anisotropy of diffusion in patients with chronic hemiparesis. We measured in the corona radiata and the cerebral peduncle in 10 patients with a chronic hemiparesis and supratentorial lesions and 10 control subjects in regions of interest. In all patients anisotropy was reduced in the coronal radiata contralateral to the hemiparesis by more than 3 SD compared to control subjects. In three patients, each of which had a severe hemiparesis, anisotropy in the cerebral peduncle was reduced by more than 3 SD compared to normal control subjects. Our findings suggest that reduced anisotropy is associated with chronic hemiparesis.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
1053-8119
pubmed:author
pubmed:copyrightInfo
Copyright 1999 Academic Press.
pubmed:issnType
Print
pubmed:volume
10
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
225-30
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1999
pubmed:articleTitle
Anisotropy of water diffusion in corona radiata and cerebral peduncle in patients with hemiparesis.
pubmed:affiliation
Institute of Neurology, University College London, London, WC1N 3BG, United Kingdom.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't