10417186

Source:http://linkedlifedata.com/resource/pubmed/id/10417186

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0015264, umls-concept:C0026926, umls-concept:C0027021, umls-concept:C0441655
pubmed:issue	8
pubmed:dateCreated	1999-8-12
pubmed:abstractText	We investigated the antimycobacterial role of myeloperoxidase (MPO), one of the most abundant granule proteins in human neutrophils. Our data indicate that purified MPO, in the presence of hydrogen peroxide, exerts a consistent killing activity against Mycobacterium tuberculosis H37Rv and against a clinical isolate. The activity is time and dose dependent and requires the presence of chloride ions in the assay medium.
pubmed:commentsCorrections	http://linkedlifedata.com/resource/pubmed/commentcorrection/10417186-1376352, http://linkedlifedata.com/resource/pubmed/commentcorrection/10417186-1398982, http://linkedlifedata.com/resource/pubmed/commentcorrection/10417186-1522389, http://linkedlifedata.com/resource/pubmed/commentcorrection/10417186-1623077, http://linkedlifedata.com/resource/pubmed/commentcorrection/10417186-1638771, http://linkedlifedata.com/resource/pubmed/commentcorrection/10417186-1879925, http://linkedlifedata.com/resource/pubmed/commentcorrection/10417186-1901338, http://linkedlifedata.com/resource/pubmed/commentcorrection/10417186-1906841, http://linkedlifedata.com/resource/pubmed/commentcorrection/10417186-2507884, http://linkedlifedata.com/resource/pubmed/commentcorrection/10417186-2575473, http://linkedlifedata.com/resource/pubmed/commentcorrection/10417186-2770507, http://linkedlifedata.com/resource/pubmed/commentcorrection/10417186-2824628, http://linkedlifedata.com/resource/pubmed/commentcorrection/10417186-3033023, http://linkedlifedata.com/resource/pubmed/commentcorrection/10417186-3040594, http://linkedlifedata.com/resource/pubmed/commentcorrection/10417186-3734462, http://linkedlifedata.com/resource/pubmed/commentcorrection/10417186-4561500, http://linkedlifedata.com/resource/pubmed/commentcorrection/10417186-6263800, http://linkedlifedata.com/resource/pubmed/commentcorrection/10417186-6325350, http://linkedlifedata.com/resource/pubmed/commentcorrection/10417186-7266662, http://linkedlifedata.com/resource/pubmed/commentcorrection/10417186-8476559, http://linkedlifedata.com/resource/pubmed/commentcorrection/10417186-8769563, http://linkedlifedata.com/resource/pubmed/commentcorrection/10417186-9187960, http://linkedlifedata.com/resource/pubmed/commentcorrection/10417186-9353042, http://linkedlifedata.com/resource/pubmed/commentcorrection/10417186-9787133
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/0246127
pubmed:citationSubset	IM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/Anti-Bacterial Agents, http://linkedlifedata.com/resource/pubmed/chemical/Hydrogen Peroxide, http://linkedlifedata.com/resource/pubmed/chemical/Peroxidase
pubmed:status	MEDLINE
pubmed:month	Aug
pubmed:issn	0019-9567
pubmed:author	pubmed-author:BanfiEE, pubmed-author:BorelliVV, pubmed-author:PerrottaM GMG, pubmed-author:ZabucchiGG
pubmed:issnType	Print
pubmed:volume	67
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	4149-52
pubmed:dateRevised	2009-11-18
pubmed:meshHeading	pubmed-meshheading:10417186-Anti-Bacterial Agents, pubmed-meshheading:10417186-Dose-Response Relationship, Drug, pubmed-meshheading:10417186-Humans, pubmed-meshheading:10417186-Hydrogen Peroxide, pubmed-meshheading:10417186-Mycobacterium tuberculosis, pubmed-meshheading:10417186-Peroxidase, pubmed-meshheading:10417186-Time Factors
pubmed:year	1999
pubmed:articleTitle	Myeloperoxidase exerts microbicidal activity against Mycobacterium tuberculosis.
pubmed:affiliation	Dipartimento di Fisiologia e Patologia, Università di Trieste, 34127 Trieste, Italy.
pubmed:publicationType	Journal Article, Research Support, Non-U.S. Gov't