Source:http://linkedlifedata.com/resource/pubmed/id/10415390
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
1999-9-28
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pubmed:abstractText |
This study determined baroreceptor reflex (BR) function in conscious rats which had received sham or electrolytic lesions of the anteroventral third ventricle (AV3V) 54-56 days previously. Resting mean arterial pressure (MAP) and heart rate (HR) values of the AV3V-lesion rats were similar to those of sham-lesion rats (P>0.05 for both comparisons). The sensitivity of the BR-mediated tachycardia in AV3V-lesion was greater than in sham-lesion rats (-9. 92+/-1.00 vs. -4.54+/-0.45 bpm/mmHg, P<0.05). The sensitivity of the BR-mediated bradycardia in AV3V-lesion rats was also greater than in rats with sham lesions (-3.56+/-0.38 vs. -2.06+/-0.42 bpm/mmHg, P<0. 05). The AV3V lesions did not affect other BR parameters. These findings demonstrate that chronic lesions of the AV3V region increase the sensitivity of the baroreceptor HR reflex in conscious rats.
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pubmed:grant | |
pubmed:keyword | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0006-8993
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pubmed:author | |
pubmed:copyrightInfo |
Copyright 1999 Published by Elsevier Science B.V.
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pubmed:issnType |
Print
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pubmed:day |
24
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pubmed:volume |
835
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
330-3
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:10415390-Animals,
pubmed-meshheading:10415390-Blood Pressure,
pubmed-meshheading:10415390-Cerebral Ventricles,
pubmed-meshheading:10415390-Heart Rate,
pubmed-meshheading:10415390-Male,
pubmed-meshheading:10415390-Pressoreceptors,
pubmed-meshheading:10415390-Rats,
pubmed-meshheading:10415390-Rats, Sprague-Dawley,
pubmed-meshheading:10415390-Reflex,
pubmed-meshheading:10415390-Time Factors
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pubmed:year |
1999
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pubmed:articleTitle |
Effects of chronic lesions of the anteroventral third ventricle region on baroreceptor reflex function in conscious rats.
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pubmed:affiliation |
Department of Pharmacology, University of Iowa, Iowa City, IA, 52242-1109, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, U.S. Gov't, Non-P.H.S.
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