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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
7
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pubmed:dateCreated |
1999-9-8
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pubmed:abstractText |
Although laboratory studies are not necessarily predictive of clinical activity; they can help to elucidate mechanisms underlying clinical activity when the latter has been established. In a recent clinical study, an essential oil mouthrinse (Listerine Antiseptic) was shown to be significantly more effective than an amine fluoride/stannous fluoride mouthrinse (Meridol) in inhibiting supragingival plaque formation. This paper reports the results of laboratory studies comparing the antimicrobial effectiveness of these 2 mouthrinses using a kill kinetics assay and a plaque biofilm kill assay. In both assays, the essential oil mouthrinse was considerably more effective than the amine fluoride/stannous fluoride mouthrinse. These findings are consistent with the results of the clinical trial and may help to explain the observed differences in clinical activity.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
D
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Amines,
http://linkedlifedata.com/resource/pubmed/chemical/Anti-Infective Agents, Local,
http://linkedlifedata.com/resource/pubmed/chemical/Coloring Agents,
http://linkedlifedata.com/resource/pubmed/chemical/Drug Combinations,
http://linkedlifedata.com/resource/pubmed/chemical/Listerine,
http://linkedlifedata.com/resource/pubmed/chemical/Meridol,
http://linkedlifedata.com/resource/pubmed/chemical/Mouthwashes,
http://linkedlifedata.com/resource/pubmed/chemical/Oils, Volatile,
http://linkedlifedata.com/resource/pubmed/chemical/Salicylates,
http://linkedlifedata.com/resource/pubmed/chemical/Terpenes,
http://linkedlifedata.com/resource/pubmed/chemical/Tin Fluorides
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0303-6979
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
26
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
474-6
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:10412853-Amines,
pubmed-meshheading:10412853-Anti-Infective Agents, Local,
pubmed-meshheading:10412853-Bacteria,
pubmed-meshheading:10412853-Biofilms,
pubmed-meshheading:10412853-Candida albicans,
pubmed-meshheading:10412853-Coloring Agents,
pubmed-meshheading:10412853-Dental Plaque,
pubmed-meshheading:10412853-Drug Combinations,
pubmed-meshheading:10412853-Fusobacterium nucleatum,
pubmed-meshheading:10412853-Humans,
pubmed-meshheading:10412853-Lactobacillus casei,
pubmed-meshheading:10412853-Mouthwashes,
pubmed-meshheading:10412853-Oils, Volatile,
pubmed-meshheading:10412853-Prevotella intermedia,
pubmed-meshheading:10412853-Salicylates,
pubmed-meshheading:10412853-Saliva,
pubmed-meshheading:10412853-Streptococcus mutans,
pubmed-meshheading:10412853-Terpenes,
pubmed-meshheading:10412853-Tin Fluorides,
pubmed-meshheading:10412853-Tongue
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pubmed:year |
1999
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pubmed:articleTitle |
Comparative antimicrobial activity of an essential oil and an amine fluoride/stannous fluoride mouthrinse in vitro.
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pubmed:affiliation |
The Warner-Lambert Company, Morris Plains, NJ 07950, USA.
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pubmed:publicationType |
Journal Article,
Comparative Study
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