Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
1999-8-5
pubmed:abstractText
An alternative concept of the relationship between morphological and elastic properties of trabecular bone is presented and applied to human tissue from several anatomical locations using a digital approach. The three-dimensional morphology of trabecular bone was assessed with a microcomputed tomography system and the method of directed secants as well as the star volume procedure were used to compute mean intercept length (MIL) and average bone length (ABL) of 4 mm cubic specimens. Assuming isotropic elastic properties for the trabecular tissue, the general elastic tensors of the bone specimens were determined using the homogenization method and the closest orthotropic tensors were calculated with an optimization algorithm. The assumption of orthotropy for trabecular bone was found to improve with specimen size and hold within 6.1 percent for a 4 mm cube size. A strong global relationship (r2 = 0.95) was obtained between fabric and the orthotropic elastic tensor with a minimal set of five constants. Mean intercept length and average bone length provided an equivalent power of prediction. These results support the hypothesis that the elastic properties of human trabecular bone from an arbitrary anatomical location can be estimated from an approximation of the anisotropic morphology and a prior knowledge of tissue properties.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0148-0731
pubmed:author
pubmed:issnType
Print
pubmed:volume
120
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
640-6
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed-meshheading:10412443-Adult, pubmed-meshheading:10412443-Aged, pubmed-meshheading:10412443-Algorithms, pubmed-meshheading:10412443-Anisotropy, pubmed-meshheading:10412443-Anthropometry, pubmed-meshheading:10412443-Bias (Epidemiology), pubmed-meshheading:10412443-Bone and Bones, pubmed-meshheading:10412443-Cadaver, pubmed-meshheading:10412443-Elasticity, pubmed-meshheading:10412443-Female, pubmed-meshheading:10412443-Finite Element Analysis, pubmed-meshheading:10412443-Humans, pubmed-meshheading:10412443-Male, pubmed-meshheading:10412443-Middle Aged, pubmed-meshheading:10412443-Models, Biological, pubmed-meshheading:10412443-Numerical Analysis, Computer-Assisted, pubmed-meshheading:10412443-Predictive Value of Tests, pubmed-meshheading:10412443-Reproducibility of Results, pubmed-meshheading:10412443-Tensile Strength, pubmed-meshheading:10412443-Tomography, X-Ray Computed
pubmed:year
1998
pubmed:articleTitle
A global relationship between trabecular bone morphology and homogenized elastic properties.
pubmed:affiliation
Orthopaedic Research Laboratories, University of Michigan, Ann Arbor 48109, USA. philippe.zysset@epfl.ch
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, Non-U.S. Gov't