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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
1999-9-2
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pubmed:abstractText |
Murine models (MRL/gld/gld mice) and recent evidence in humans suggest a possible role of Fas and Fas ligand (Fas-L) germline mutations in the pathogenesis of autoimmune-related lymphoproliferation, including adult cases. In this study, the presence of Fas and Fas-L germline mutations was investigated in a consecutive series of adult patients with lymphoproliferative disorders occurring in the context of Sjögren's syndrome (SS) and type II mixed cryoglobulinemia (MC).
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
0392-856X
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
17
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
339-42
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:10410268-Aged,
pubmed-meshheading:10410268-Antigens, CD95,
pubmed-meshheading:10410268-Cryoglobulinemia,
pubmed-meshheading:10410268-DNA Mutational Analysis,
pubmed-meshheading:10410268-Fas Ligand Protein,
pubmed-meshheading:10410268-Female,
pubmed-meshheading:10410268-Gene Amplification,
pubmed-meshheading:10410268-Germ-Line Mutation,
pubmed-meshheading:10410268-Humans,
pubmed-meshheading:10410268-Leukocytes, Mononuclear,
pubmed-meshheading:10410268-Lymphoma,
pubmed-meshheading:10410268-Lymphoproliferative Disorders,
pubmed-meshheading:10410268-Membrane Glycoproteins,
pubmed-meshheading:10410268-Middle Aged,
pubmed-meshheading:10410268-Polymerase Chain Reaction,
pubmed-meshheading:10410268-Polymorphism, Single-Stranded Conformational,
pubmed-meshheading:10410268-Sjogren's Syndrome
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pubmed:articleTitle |
Lack of Fas and Fas-L mutations in patients with lymphoproliferative disorders associated with Sjögren's syndrome and type II mixed cryoglobulinemia.
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pubmed:affiliation |
Division of Experimental Oncology I, Centro di Riferimento Oncologico, Aviano, Italy.
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pubmed:publicationType |
Journal Article
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