Linked Life Data

10407407

Source:http://linkedlifedata.com/resource/pubmed/id/10407407

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
8
pubmed:dateCreated
1999-9-14
pubmed:abstractText
A recent model proposed that N-glycans serve as apical targeting signals for soluble and membrane proteins in epithelial cells and neurons by interacting with lectin sorters in the trans-Golgi network. However, we believe that a number of experimental observations support an alternative hypothesis, that N-glycans play a facilitative role, by providing structural support or preventing aggregation of the proteins for example, thereby allowing interaction of proteinaceous apical sorting signals with the sorting machinery. This article discusses the experimental data currently available and how they relate to the proposed models.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
0962-8924
pubmed:author
pubmed:issnType
Print
pubmed:volume
9
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
291-4
pubmed:dateRevised
2011-3-18
pubmed:meshHeading
pubmed:year
1999
pubmed:articleTitle
Glycans in post-Golgi apical targeting: sorting signals or structural props?
pubmed:affiliation
Dyson Vision Institute, Depts of Ophthalmology and Cell Biology, Weill Medical College of Cornell University, New York, USA. boulan@mail.med.cornell.edu
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Review, Research Support, Non-U.S. Gov't