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PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1-2
pubmed:dateCreated
1999-9-10
pubmed:abstractText
Ontogenetic development of FMRFamide immunoreactivity in the cells and nerve fibers of the pituitary was studied in the tree shrew Tupaia belangeri. Up to the 26th day of gestation (E26), no FMRFamide immunoreactivity was visible. From E27 onwards it increased continuously until prenatally, on E41, the adult pattern was reached in the adenohypophysis, although at a lower intensity. In the adult Tupaia, as in the other mammals studied so far, a finely stained FMRFamide-immunoreactive fiber network was visible in the neural lobe and the infundibular stalk. As in several other adult mammals including man, endocrine cells in the pars intermedia and numerous scattered cells in the pars distalis were labeled, in contrast to several reports on rats and our studies on Galago, showing no FMRFamide-immunoreactive cells in these locations of the pituitary. With reference to the 'basophil invasion', we found FMRFamide-immunoreactive endocrine cells invading the neural lobe from the pars intermedia during the pituitary development. The distribution pattern of FMRFamide immunoreactivity in Tupaia indicates that the mammalian counterparts of FMRFamide may function as neuromodulators, neurotransmitters or as hormones already in defined prenatal stages.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
0006-8993
pubmed:author
pubmed:copyrightInfo
Copyright 1999 Elsevier Science B.V.
pubmed:issnType
Print
pubmed:day
10
pubmed:volume
834
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
83-8
pubmed:dateRevised
2007-11-15
pubmed:meshHeading
pubmed:year
1999
pubmed:articleTitle
FMRFamide immunoreactivity and the invasion of adenohypophyseal cells into the neural lobe in the developing pituitary of the tree shrew Tupaia belangeri.
pubmed:affiliation
Department of Morphology, Center of Anatomy, School of Medicine, University of Göttingen, Kreuzbergring 36, D-37075, Göttingen, Germany.
pubmed:publicationType
Journal Article