Linked Life Data

10406685

Source:http://linkedlifedata.com/resource/pubmed/id/10406685

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
pubmed:issue
3-4
pubmed:dateCreated
1999-8-17
pubmed:abstractText
The surface properties of stents can be modified by coating them, for example with a polymer. Phosphorylcoline (PC) is the major component of the outer layer of the cell membrane. The haemo- and biocompatibility of a PC-containing polymer is thus based on biomimicry, and has been confirmed by several experiments showing much reduced thrombogenicity of PC-coated surfaces, and porcine coronary artery implants showing no sign of adverse effect. Clinical experience with the PC-coated BiodivYsio appears favourable. The PC coating can be tailored for take up and controlled elution of various drugs for stent-based local delivery, a property which is being actively explored.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
1084-2764
pubmed:author
pubmed:issnType
Print
pubmed:volume
3
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
149-50
pubmed:dateRevised
2005-11-16
pubmed:meshHeading
pubmed:articleTitle
Biomimicry 1: PC.
pubmed:affiliation
Cardiovascular Group, Clinical Sciences Centre, Northern General Hospital, Sheffield, UK. d.c.cumberland@sheffield.ac.uk
pubmed:publicationType
Journal Article, Review