|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
13
|
|
pubmed:dateCreated |
1999-10-14
|
|
pubmed:abstractText |
Histamine was converted to a selective histamine H3-receptor antagonist by capping the primary amine with 2-naphthalenesulfonyl chloride. Higher receptor affinity and lower variability in the data from the various bioassays were achieved with the 2-naphthalensulfonamides of histamine homologues.
|
|
pubmed:commentsCorrections |
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Jul
|
|
pubmed:issn |
0960-894X
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:day |
5
|
|
pubmed:volume |
9
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
1825-30
|
|
pubmed:dateRevised |
2003-11-14
|
|
pubmed:meshHeading |
pubmed-meshheading:10406649-Animals,
pubmed-meshheading:10406649-Drug Design,
pubmed-meshheading:10406649-Guinea Pigs,
pubmed-meshheading:10406649-Histamine Antagonists,
pubmed-meshheading:10406649-Imidazoles,
pubmed-meshheading:10406649-Kinetics,
pubmed-meshheading:10406649-Models, Chemical,
pubmed-meshheading:10406649-Receptors, Histamine H3,
pubmed-meshheading:10406649-Sulfonamides
|
|
pubmed:year |
1999
|
|
pubmed:articleTitle |
From histamine to imidazolylalkyl-sulfonamides: the design of a novel series of histamine H3-receptor antagonists.
|
|
pubmed:affiliation |
The James Black Foundation, London, UK. matthew.tozer@kcl.ac.uk
|
|
pubmed:publicationType |
Journal Article
|
