Linked Life Data

10403342

Source:http://linkedlifedata.com/resource/pubmed/id/10403342

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
1999-7-28
pubmed:abstractText
Oral rehydration solution (ORS) is lifesaving therapy for cholera and pediatric diarrhea. During a cholera epidemic in Guinea-Bissau, we evaluated the microbiologic quality of ORS prepared at a hospital and tested a simple intervention using special vessels for disinfecting tap water with bleach and for preparing, storing, and dispensing ORS. Few coliform bacteria and Escherichia coli were recovered from tap water; however, pre-intervention ORS contained numerous bacteria including E. coli and toxigenic Vibrio cholerae O1. In contrast, ORS samples from intervention vessels had few or no coliform bacteria, no E. coli, and no V. cholerae. Mean pre-intervention counts of coliform bacteria (3.4 x 10(7) colony-forming units [cfu]/100 ml) and E. coli (6.2 x 10(3) cfu) decreased significantly during the intervention period to 3.6 x 10(2) cfu and 0 cfu, respectively (P < 0.001). This simple system using bleach disinfectant and special storage vessels prevents bacterial contamination of ORS and reduces the risk of nosocomial transmission of cholera and other enteric pathogens.
pubmed:keyword
http://linkedlifedata.com/resource/pubmed/keyword/Africa, http://linkedlifedata.com/resource/pubmed/keyword/Africa South Of The Sahara, http://linkedlifedata.com/resource/pubmed/keyword/Bacterial And Fungal Diseases, http://linkedlifedata.com/resource/pubmed/keyword/CHOLERA, http://linkedlifedata.com/resource/pubmed/keyword/DIARRHEA, http://linkedlifedata.com/resource/pubmed/keyword/Developing Countries, http://linkedlifedata.com/resource/pubmed/keyword/Diseases, http://linkedlifedata.com/resource/pubmed/keyword/EPIDEMICS, http://linkedlifedata.com/resource/pubmed/keyword/Guinea-bissau, http://linkedlifedata.com/resource/pubmed/keyword/Infections, http://linkedlifedata.com/resource/pubmed/keyword/Oral Rehydration, http://linkedlifedata.com/resource/pubmed/keyword/Portuguese Speaking Africa, http://linkedlifedata.com/resource/pubmed/keyword/Research Report, http://linkedlifedata.com/resource/pubmed/keyword/Treatment, http://linkedlifedata.com/resource/pubmed/keyword/Western Africa
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
0002-9637
pubmed:author
pubmed:issnType
Print
pubmed:volume
60
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1051-5
pubmed:dateRevised
2004-11-17
pubmed:otherAbstract
PIP: This paper evaluates the microbiologic quality of oral rehydration solution (ORS) prepared at a hospital during a cholera epidemic in Guinea-Bissau. The study tested a simple intervention using special vessels for disinfecting tap water with bleach and for preparing, storing, and dispensing ORS. Subjects included approximately 80% of the cholera patients seeking treatment, who were referred to the cholera ward of Simao-Mendes National Hospital. Results suggest that only few coliform bacteria and Escherichia coli were recovered from tap water; however, pre-intervention ORS contained numerous bacteria including E. coli and toxigenic Vibrio cholerae O1. In contrast, ORS samples from intervention vessels had few or no coliform bacteria, no E. coli, and no V. cholerae. This simple system using bleach disinfectant and special storage vessels prevents bacterial contamination of ORS and reduces the risk of nosocomial transmission of cholera and other enteric pathogens.
pubmed:meshHeading
pubmed:year
1999
pubmed:articleTitle
First do no harm: making oral rehydration solution safer in a cholera epidemic.
pubmed:affiliation
Foodborne and Diarrheal Diseases Branch, Division of Bacterial and Mycotic Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA.
pubmed:publicationType
Journal Article