|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
7
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|
pubmed:dateCreated |
1999-7-20
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|
pubmed:abstractText |
To examine the safety and pharmacokinetics of and clinical response to leflunomide, a de novo pyrimidine synthesis inhibitor, when administered to patients with active rheumatoid arthritis (RA) who have been receiving long-term methotrexate therapy.
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pubmed:language |
eng
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|
pubmed:journal |
|
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pubmed:citationSubset |
AIM
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pubmed:chemical |
|
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pubmed:status |
MEDLINE
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|
pubmed:month |
Jul
|
|
pubmed:issn |
0004-3591
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|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
42
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
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|
pubmed:pagination |
1322-8
|
|
pubmed:dateRevised |
2006-11-15
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|
pubmed:meshHeading |
pubmed-meshheading:10403258-Adult,
pubmed-meshheading:10403258-Alanine Transaminase,
pubmed-meshheading:10403258-Anti-Inflammatory Agents, Non-Steroidal,
pubmed-meshheading:10403258-Arthritis, Rheumatoid,
pubmed-meshheading:10403258-Aspartate Aminotransferases,
pubmed-meshheading:10403258-Diarrhea,
pubmed-meshheading:10403258-Drug Therapy, Combination,
pubmed-meshheading:10403258-Female,
pubmed-meshheading:10403258-Humans,
pubmed-meshheading:10403258-Isoxazoles,
pubmed-meshheading:10403258-Liver,
pubmed-meshheading:10403258-Male,
pubmed-meshheading:10403258-Methotrexate,
pubmed-meshheading:10403258-Middle Aged,
pubmed-meshheading:10403258-Nausea,
pubmed-meshheading:10403258-Patient Compliance,
pubmed-meshheading:10403258-Treatment Outcome
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|
pubmed:year |
1999
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|
pubmed:articleTitle |
Pharmacokinetics, safety, and efficacy of combination treatment with methotrexate and leflunomide in patients with active rheumatoid arthritis.
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|
pubmed:affiliation |
Brigham and Women's Hospital, Boston, Massachusetts 02115, USA.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Research Support, Non-U.S. Gov't,
Multicenter Study
|
