Source:http://linkedlifedata.com/resource/pubmed/id/10402980
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
1
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| pubmed:dateCreated |
1999-9-8
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| pubmed:abstractText |
Malignant melanoma of the head and neck can metastasize to lymph nodes within the parotid gland. Selective lymphadenectomy is the modern method of staging regional lymph node basins in clinically localized melanoma. This procedure involves intraoperative lymphatic mapping and directed, selective removal of the first draining nodes or sentinel lymph nodes (SLNs). Historically, the assessment of parotid lymph nodes would involve a superficial parotidectomy with facial nerve dissection. Since 1993, 28 patients with localized melanoma of the head and neck have demonstrated lymphatic drainage to parotid lymph nodes on preoperative lymphoscintigraphy. The overall success rate of parotid selective lymphadenectomy is 86% (24 of 28 patients). Of the 28 patients, there were 6 early patients in whom blue dye alone was utilized intraoperatively, and the success rate is 50% (3 of 6 patients). When blue dye and radiocolloid mapping techniques are combined, the parotid selective lymphadenectomy is successful in 95% of patients (21 of 22 patients). Four of the 24 patients (17%) had metastases to the SLNs and underwent therapeutic superficial parotidectomy and/or modified radical neck dissection. After completion of the therapeutic superficial parotidectomy, 1 of the 4 patients was found to have an additional parotid (nonsentinel) node with melanoma metastases. None of the patients incurred injury to the facial nerve by parotid selective lymphadenectomy. To date, 2 of 28 patients (7%) have had regional recurrence to the parotid gland. Failure of the SLN technique may occur when blue dye alone is used, when human serum albumin (not sulfur colloid) is the radiocolloid, when prior wide excision and skin graft is present before lymphatic mapping, and when all SLNs are not retrieved. We conclude that parotid selective lymphadenectomy is a safe and reliable alternative to superficial parotidectomy for staging clinically localized melanoma of the head and neck.
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| pubmed:language |
eng
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| pubmed:journal | |
| pubmed:citationSubset |
IM
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| pubmed:status |
MEDLINE
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| pubmed:month |
Jul
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| pubmed:issn |
0148-7043
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| pubmed:author | |
| pubmed:issnType |
Print
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| pubmed:volume |
43
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| pubmed:owner |
NLM
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| pubmed:authorsComplete |
Y
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| pubmed:pagination |
1-6
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| pubmed:dateRevised |
2004-11-17
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| pubmed:meshHeading |
pubmed-meshheading:10402980-Adult,
pubmed-meshheading:10402980-Aged,
pubmed-meshheading:10402980-Aged, 80 and over,
pubmed-meshheading:10402980-Female,
pubmed-meshheading:10402980-Follow-Up Studies,
pubmed-meshheading:10402980-Head and Neck Neoplasms,
pubmed-meshheading:10402980-Humans,
pubmed-meshheading:10402980-Lymph Node Excision,
pubmed-meshheading:10402980-Lymph Nodes,
pubmed-meshheading:10402980-Lymphatic Metastasis,
pubmed-meshheading:10402980-Male,
pubmed-meshheading:10402980-Melanoma,
pubmed-meshheading:10402980-Middle Aged,
pubmed-meshheading:10402980-Neoplasm Recurrence, Local,
pubmed-meshheading:10402980-Neoplasm Staging,
pubmed-meshheading:10402980-Parotid Gland,
pubmed-meshheading:10402980-Parotid Neoplasms,
pubmed-meshheading:10402980-Reoperation,
pubmed-meshheading:10402980-Retrospective Studies,
pubmed-meshheading:10402980-Skin Neoplasms
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| pubmed:year |
1999
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| pubmed:articleTitle |
Parotid selective lymphadenectomy in malignant melanoma.
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| pubmed:affiliation |
Division of Plastic Surgery, University of South Florida College of Medicine, H. Lee Moffitt Cancer Center and Research Institute, Tampa, USA.
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| pubmed:publicationType |
Journal Article
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