Linked Life Data

10402661

Source:http://linkedlifedata.com/resource/pubmed/id/10402661

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
1999-8-13
pubmed:abstractText
It was established, that the content of nicotinamide adenine dinucleotides and the binding of NAD by isolated brain cortex synaptic membranes under experimental parkinsonism are impaired. Treatment of the experimental results in the Scatchard plots for binding of [U-14C]NAD to the brain cortex synaptic membranes demonstrated that binding capacities lowered, without changes of affinities. NAD-glycohydrolase involved in development of this pathology. The modulative effect of in vivo administered NAm and nicotinoyl-GABA supposes that NAm acts via NAD which binds specifically with synaptic membranes. Thus, NAm and nicotinoyl-GABA are involved in the regulation of the processes in the brain under experimental parkinsonism.
pubmed:language
ukr
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0201-8470
pubmed:author
pubmed:issnType
Print
pubmed:volume
70
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
126-31
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:articleTitle
[Neurotrophic action of nicotinamide and nicotinoyl-GABA in rat brain in experimental Parkinsonism].
pubmed:affiliation
A.V. Palladin Institute of Biochemistry, NAS of Ukraine, Kyiv.
pubmed:publicationType
Journal Article, English Abstract