rdf:type |
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lifeskim:mentions |
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pubmed:issue |
7
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pubmed:dateCreated |
1999-9-13
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pubmed:abstractText |
Maize leaves have a stereotypical pattern of cell types organized into discrete domains. These domains are altered by mutations in knotted1 (kn1) and knox (for kn1-like homeobox) genes. Gnarley (Gn1) is a dominant maize mutant that exhibits many of the phenotypic characteristics of the kn1 family of mutants. Gn1 is unique because it changes parameters of cell growth in the basal-most region of the leaf, the sheath, resulting in dramatically altered sheath morphology. The strongly expressive allele Gn1-R also gives rise to a floral phenotype in which ectopic carpels form. Introgression studies showed that the severity of the Gn1-conferred phenotype is strongly influenced by genetic background. Gn1 maps to knox4, and knox4 is ectopically expressed in plants with the Gn1-conferred phenotype. Immunolocalization experiments showed that the KNOX protein accumulates at the base of Gn1 leaves in a pattern that is spatially and temporally correlated with appearance of the mutant phenotype. We further demonstrate that Gn1 is knox4 by correlating loss of the mutant phenotype with insertion of a Mutator transposon into knox4.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/10402426-10022841,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10402426-11038553,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10402426-1313711,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10402426-1333722,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10402426-1362381,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10402426-16453866,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10402426-1672445,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10402426-17246303,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10402426-17246413,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10402426-2088734,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10402426-2391003,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10402426-7557382,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10402426-7684007,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10402426-7715728,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10402426-7734963,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10402426-7866030,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10402426-7896105,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10402426-8103379,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10402426-8103599,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10402426-8138166,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10402426-8538741,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10402426-8625799,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10402426-8625845,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10402426-8631155,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10402426-8674408,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10402426-8970728,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10402426-8978070,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10402426-9254931,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10402426-9272946,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10402426-9286690,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10402426-9362467,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10402426-9367429,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10402426-9437860,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10402426-9655808,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10402426-9847244
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pubmed:language |
eng
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pubmed:journal |
|
pubmed:citationSubset |
IM
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pubmed:chemical |
|
pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
1040-4651
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pubmed:author |
|
pubmed:issnType |
Print
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pubmed:volume |
11
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1239-52
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pubmed:dateRevised |
2010-9-13
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pubmed:meshHeading |
pubmed-meshheading:10402426-Alleles,
pubmed-meshheading:10402426-Amino Acid Sequence,
pubmed-meshheading:10402426-Genes, Dominant,
pubmed-meshheading:10402426-Genes, Homeobox,
pubmed-meshheading:10402426-Homeodomain Proteins,
pubmed-meshheading:10402426-Molecular Sequence Data,
pubmed-meshheading:10402426-Mutation,
pubmed-meshheading:10402426-Plant Leaves,
pubmed-meshheading:10402426-Plant Proteins,
pubmed-meshheading:10402426-Sequence Homology, Amino Acid,
pubmed-meshheading:10402426-Zea mays
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pubmed:year |
1999
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pubmed:articleTitle |
Gnarley1 is a dominant mutation in the knox4 homeobox gene affecting cell shape and identity.
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pubmed:affiliation |
Department of Plant and Microbial Biology, University of California, Berkeley, California 94720, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, Non-P.H.S.,
Research Support, Non-U.S. Gov't
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