rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
2
|
pubmed:dateCreated |
1999-8-18
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pubmed:abstractText |
Three patients, aged five to 16 years, developed chorea as the only or main clinical manifestation of primary antiphospholipid syndrome. In two cases, complaints were self-limited five to eight months after onset. In one patient, the clinical course was complicated by valvulitis. Under corticosteroid treatment, chorea disappeared and cardiac involvement stabilised. Primary antiphospholipid syndrome is a probably under-recognised differential diagnosis of choreatic syndromes in childhood. Assessment of anticardiolipin antibodies and/or lupus anticoagulant should be an obligatory part of the diagnostic work-up of such patients. Early diagnosis of primary antiphospholipid syndrome may improve clinical management and prognosis.
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
|
pubmed:citationSubset |
IM
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pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Apr
|
pubmed:issn |
0174-304X
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pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
30
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
96-8
|
pubmed:dateRevised |
2008-1-16
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pubmed:meshHeading |
pubmed-meshheading:10401693-Adolescent,
pubmed-meshheading:10401693-Adrenal Cortex Hormones,
pubmed-meshheading:10401693-Antibodies, Anticardiolipin,
pubmed-meshheading:10401693-Antibodies, Antinuclear,
pubmed-meshheading:10401693-Antiphospholipid Syndrome,
pubmed-meshheading:10401693-Aspirin,
pubmed-meshheading:10401693-Child, Preschool,
pubmed-meshheading:10401693-Chorea,
pubmed-meshheading:10401693-Female,
pubmed-meshheading:10401693-Heart Valves,
pubmed-meshheading:10401693-Humans,
pubmed-meshheading:10401693-Lupus Coagulation Inhibitor,
pubmed-meshheading:10401693-Male,
pubmed-meshheading:10401693-Remission, Spontaneous,
pubmed-meshheading:10401693-Thrombocytopenia,
pubmed-meshheading:10401693-Treatment Outcome
|
pubmed:year |
1999
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pubmed:articleTitle |
Chorea as the presenting clinical feature of primary antiphospholipid syndrome in childhood.
|
pubmed:affiliation |
Department of Paediatrics, University of Innsbruck, Austria.
|
pubmed:publicationType |
Journal Article,
Review,
Case Reports
|