Source:http://linkedlifedata.com/resource/pubmed/id/10397901
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
1
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| pubmed:dateCreated |
2000-10-2
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| pubmed:abstractText |
Silver negative ions (Ag-) were implanted to an insulator, polystyrene, in a relatively low ion energy ranging from 5 to 30 keV, and in a dose ranging from 10(14) to 6 x 10(16) ions. cm-2. Surfaces of Ag--implanted polystyrene were studied by means of secondary ion mass spectrometry, X-ray photoelectron spectroscopy, Fourier transform infrared spectroscopy, and micro-Raman spectroscopy, and contact angle measurement. As a result of Ag- implantation, the polystyrene surfaces underwent degradation, thereby becoming more hydrophilic with increasing dose and ion energy except an ion energy of 30 keV. The Ag- implantation in polystyrene led to enhanced growth of human vascular endothelial cells, which grew to more extent with increased hydrophilicity of Ag--implanted surfaces except an ion energy of 30 keV. Polystyrene surfaces on which Ag- were implanted up to an ion energy of 30 keV caused the same hydrophobic level as polystyrene surface itself. Nevertheless, the Ag--implanted polystyrene showed relatively good biocompatibility different from polystyrene. Such an improvement in cell adhesion may be related to the formation of a graphite-like structure on polystyrene surfaces by a Ag--implanted process. Moreover, upon plating in a high cell density, human vascular endothelial cells survived even on the polystyrene region of Ag--implanted polystyrene for longer than 1.5 months, while the cells did not grow on untreated polystyrene in the same culture conditions.
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| pubmed:language |
eng
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| pubmed:journal | |
| pubmed:citationSubset |
IM
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| pubmed:chemical | |
| pubmed:status |
MEDLINE
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| pubmed:month |
Jan
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| pubmed:issn |
0021-9304
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| pubmed:author | |
| pubmed:copyrightInfo |
Copyright 1999 John Wiley & Sons, Inc.
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| pubmed:issnType |
Print
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| pubmed:volume |
44
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| pubmed:owner |
NLM
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| pubmed:authorsComplete |
Y
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| pubmed:pagination |
22-30
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| pubmed:dateRevised |
2004-11-17
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| pubmed:meshHeading |
pubmed-meshheading:10397901-Biocompatible Materials,
pubmed-meshheading:10397901-Cell Culture Techniques,
pubmed-meshheading:10397901-Cell Division,
pubmed-meshheading:10397901-Cells, Cultured,
pubmed-meshheading:10397901-Endothelium, Vascular,
pubmed-meshheading:10397901-Humans,
pubmed-meshheading:10397901-Polystyrenes,
pubmed-meshheading:10397901-Silver,
pubmed-meshheading:10397901-Surface Properties,
pubmed-meshheading:10397901-Umbilical Veins
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| pubmed:year |
1999
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| pubmed:articleTitle |
Enhanced growth of human vascular endothelial cells on negative ion (Ag-)-implanted hydrophobic surfaces.
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| pubmed:affiliation |
Department of Polymer Chemistry, Graduate School of Engineering, Kyoto University, Kyoto 606-8501, Japan.
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| pubmed:publicationType |
Journal Article
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