Linked Life Data

10396615

Source:http://linkedlifedata.com/resource/pubmed/id/10396615

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
15
pubmed:dateCreated
1999-7-19
pubmed:abstractText
The feedback pathway from HCs to cones forms the basis of the surround responses of the bipolar cells and is essential for the spectral opponency of horizontal cells. The nature of this feedback pathway is an issue of debate. Three hypothesis are presented in literature: (1) a GABAA-ergic feedback pathway; (2) a GABA-independent feedback pathway that modulates the Ca-current in cones; and (3) an electrical feedback pathway. In this review the evidence for the various pathways will be discussed. The conclusion is that the available evidence favors the hypothesis that feedback modulates the Ca-current in the cones in a GABA independent way. An alternative role of GABA in the outer plexiform layer is discussed and finally the functional consequences of the negative feedback pathway from horizontal cells to cones are presented.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
0042-6989
pubmed:author
pubmed:issnType
Print
pubmed:volume
39
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
2449-68
pubmed:dateRevised
2008-11-21
pubmed:meshHeading
pubmed:year
1999
pubmed:articleTitle
The feedback pathway from horizontal cells to cones. A mini review with a look ahead.
pubmed:affiliation
Graduate School of Neurosciences Amsterdam, The Netherlands Ophthalmic Research Institute, Amsterdam, The Netherlands. m.kamermans@ioi.knaw.nl
pubmed:publicationType
Journal Article, Review