Source:http://linkedlifedata.com/resource/pubmed/id/10391494
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
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pubmed:dateCreated |
1999-8-19
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pubmed:abstractText |
The aim was to test the hypothesis that 5-hydroxytryptamine (5-HT) influences the microcirculation of the masseter muscle. Rabbit masseters were infused with increasing concentrations of 5-HT (10(-9)-10(-5) M) on the experimental side and with saline on the control side. The effect on microcirculatory blood flow was measured by laser-Doppler flowmetry. The intramuscular temperature was recorded to monitor the influence of tissue temperature. 5-HT infusion resulted in a statistically significant decrease in blood flow at the lowest concentration (10(-9) M) (median; -11.2%: Wilcoxon signed-rank test; p<0.05). At concentrations greater than 10(-9) M, there was no significant change in blood flow. This study shows a decrease of microcirculatory blood flow in the rabbit masseter following 5-HT infusion (10(-9) M).
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
D
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
0003-9969
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
44
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
377-82
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pubmed:dateRevised |
2003-11-14
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pubmed:meshHeading |
pubmed-meshheading:10391494-Animals,
pubmed-meshheading:10391494-Body Temperature,
pubmed-meshheading:10391494-Dose-Response Relationship, Drug,
pubmed-meshheading:10391494-Extracellular Space,
pubmed-meshheading:10391494-Infusion Pumps,
pubmed-meshheading:10391494-Injections, Intramuscular,
pubmed-meshheading:10391494-Laser-Doppler Flowmetry,
pubmed-meshheading:10391494-Male,
pubmed-meshheading:10391494-Masseter Muscle,
pubmed-meshheading:10391494-Microcirculation,
pubmed-meshheading:10391494-Rabbits,
pubmed-meshheading:10391494-Serotonin,
pubmed-meshheading:10391494-Sodium Chloride
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pubmed:year |
1999
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pubmed:articleTitle |
Effect of 5-hydroxytryptamine infusion on microcirculation in the rabbit masseter muscle measured by laser-Doppler flowmetry.
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pubmed:affiliation |
Department of Clinical Oral Physiology, Faculty of Dentistry, Karolinska Institutet, Huddinge, Sweden. hkurita@hsp.md.shinshu-u.ac.jp
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pubmed:publicationType |
Journal Article
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