Source:http://linkedlifedata.com/resource/pubmed/id/10389062
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
2
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| pubmed:dateCreated |
1999-8-11
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| pubmed:abstractText |
A prospective cohort study was undertaken with two end points: (i) to compare the 48 h time cut-off with the carrier state criterion for classifying infections, and (ii) to determine a time cut-off more in line with the carrier state concept. All patients admitted to the intensive care unit and expected to require mechanical ventilation for a period > or = 3 days were enrolled. Surveillance cultures of throat and rectum were obtained on admission and thereafter twice weekly to distinguish micro-organisms that were imported into the intensive care unit from those acquired during the stay in the unit. A total of 117 patients with median age of 61 years and median Simplified Acute Physiology Score II of 42, were included in the study. Of these patients, 48 (41%) developed a total of 74 infection episodes. Using the 48 h cut-off point, 80% of all infections were classified as ICU-acquired. According to the carrier state criterion, 44 infections (60%) were of primary endogenous development caused by micro-organisms imported into the intensive care unit. Seventeen secondary endogenous (23%) and 13 exogenous (17%) infections were caused by bacteria acquired in the unit. The carrier state classification allowed the transfer of 49% of infections from the ICU-acquired group into the import group. A time cut-off of nine days was found to identify ICU-acquired infections better than two days. These data suggest that monitoring of carriage of micro-organisms may be a more realistic approach to classify infections developing in the intensive care unit.
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| pubmed:language |
eng
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| pubmed:journal | |
| pubmed:citationSubset |
IM
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| pubmed:status |
MEDLINE
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| pubmed:month |
Jun
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| pubmed:issn |
0195-6701
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| pubmed:author | |
| pubmed:issnType |
Print
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| pubmed:volume |
42
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| pubmed:owner |
NLM
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| pubmed:authorsComplete |
Y
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| pubmed:pagination |
125-33
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| pubmed:dateRevised |
2004-11-17
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| pubmed:meshHeading |
pubmed-meshheading:10389062-Adult,
pubmed-meshheading:10389062-Aged,
pubmed-meshheading:10389062-Carrier State,
pubmed-meshheading:10389062-Cohort Studies,
pubmed-meshheading:10389062-Community-Acquired Infections,
pubmed-meshheading:10389062-Cross Infection,
pubmed-meshheading:10389062-Female,
pubmed-meshheading:10389062-Humans,
pubmed-meshheading:10389062-Intensive Care Units,
pubmed-meshheading:10389062-Italy,
pubmed-meshheading:10389062-Likelihood Functions,
pubmed-meshheading:10389062-Male,
pubmed-meshheading:10389062-Middle Aged,
pubmed-meshheading:10389062-Prospective Studies,
pubmed-meshheading:10389062-ROC Curve,
pubmed-meshheading:10389062-Respiration, Artificial
|
| pubmed:year |
1999
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| pubmed:articleTitle |
Are most ICU infections really nosocomial? A prospective observational cohort study in mechanically ventilated patients.
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| pubmed:affiliation |
Department of Anaesthesia and Intensive Care, University of Trieste, Italy.
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| pubmed:publicationType |
Journal Article
|