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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
5
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pubmed:dateCreated |
1999-8-17
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pubmed:abstractText |
Acute renal failure complicating open heart surgery is not uncommon. Dopamine infusion (2.5-4.0 microg/kg per min) has often been advocated for prophylactic 'renal protection' in this setting despite little objective evidence of real benefit. We aimed to investigate whether dopamine offers any 'renal protection' in patients with normal heart and kidney functions undergoing routine coronary artery bypass grafting (CABG). Urinary excretion of retinol-binding protein (RBP), previously validated as a sensitive and accurate marker of early renal tubular injury, was used to assess the renal effects of dopamine during the first postoperative week.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
1010-7940
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
15
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
717-21; discussion 721-2
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pubmed:dateRevised |
2010-11-18
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pubmed:meshHeading |
pubmed-meshheading:10386423-Acute Kidney Injury,
pubmed-meshheading:10386423-Adult,
pubmed-meshheading:10386423-Aged,
pubmed-meshheading:10386423-Cardiotonic Agents,
pubmed-meshheading:10386423-Coronary Artery Bypass,
pubmed-meshheading:10386423-Dopamine,
pubmed-meshheading:10386423-Dose-Response Relationship, Drug,
pubmed-meshheading:10386423-Female,
pubmed-meshheading:10386423-Humans,
pubmed-meshheading:10386423-Kidney Function Tests,
pubmed-meshheading:10386423-Kidney Tubules,
pubmed-meshheading:10386423-Male,
pubmed-meshheading:10386423-Middle Aged,
pubmed-meshheading:10386423-Preoperative Care,
pubmed-meshheading:10386423-Prospective Studies,
pubmed-meshheading:10386423-Reference Values,
pubmed-meshheading:10386423-Retinol-Binding Proteins,
pubmed-meshheading:10386423-Statistics, Nonparametric,
pubmed-meshheading:10386423-Surgical Procedures, Elective,
pubmed-meshheading:10386423-Treatment Outcome
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pubmed:year |
1999
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pubmed:articleTitle |
The effect of 'renal-dose' dopamine on renal tubular function following cardiac surgery: assessed by measuring retinol binding protein (RBP).
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pubmed:affiliation |
Department of Cardiothoracic Surgery, Wythenshawe Hospital, Manchester, UK. gustm-tang@aol.com
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Comparative Study,
Randomized Controlled Trial
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