Source:http://linkedlifedata.com/resource/pubmed/id/10382577
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
6
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pubmed:dateCreated |
1999-7-15
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pubmed:abstractText |
Longitudinal assessment of risk factors for periodontal disease is necessary to provide evidence that a putative risk factor or risk indicator is a true risk factor. The purpose of the present study was to explore longitudinally a variety of markers as possible periodontal risk factors in subjects with little or no periodontal disease at baseline. 415 subjects with mild or little periodontal disease were examined: medical and dental history; socioeconomic profile, clinical measurements, microbial samples and radiographic assessment of bone height were performed at baseline, and at a follow-up examination 2 to 5 years later. Mean probing pocket depth (PPD) at baseline was 1.99+/-0.37 mm while mean overall change was 0.1 mm which amounts to an annual rate of 0.04 mm. Overall mean clinical attachment level (1.75+/-0.6 mm) at baseline resulted in mean attachment change of 0.28 mm (0.12 mm annually). Alveolar crestal height (ACH) at baseline (mean 2.05+/-0.85 mm) resulting in a mean net loss of 0.1 mm. Approximately 10% of all sites presented for the second visit with attachment loss exceeding the threshold (4.4% annually), while only 2.2% of all sites exhibited attachment gain (0.88% annually). Older individuals exhibited greater mean bone loss but the least amount of attachment loss. Current smokers exhibited greater disease progression compared to non-smokers. Tooth morbidity (0.17 teeth/patient/year) was associated with greater baseline CAL and ACH loss, and an assortment of systemic conditions. Subjects who harbored Bacteroides forsythus (Bf) at baseline had greater loss in ACH; likewise, these subjects experienced greater proportions of losing sites and twice as much tooth mortality compared to Bf-negative patients. Baseline clinical parameters correlated strongly with the outcome, i.e., subjects with deeper mean pocket depth at baseline exhibited greater increase in pocket depth overtime; while subjects with greater attachment loss at baseline exhibited greater attachment loss between the 1st and 2nd visits.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
D
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0303-6979
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
26
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
374-80
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:10382577-Adult,
pubmed-meshheading:10382577-Aged,
pubmed-meshheading:10382577-Alveolar Bone Loss,
pubmed-meshheading:10382577-Analysis of Variance,
pubmed-meshheading:10382577-Biological Markers,
pubmed-meshheading:10382577-Dental Plaque,
pubmed-meshheading:10382577-Disease Progression,
pubmed-meshheading:10382577-Female,
pubmed-meshheading:10382577-Humans,
pubmed-meshheading:10382577-Longitudinal Studies,
pubmed-meshheading:10382577-Male,
pubmed-meshheading:10382577-Middle Aged,
pubmed-meshheading:10382577-Periodontal Attachment Loss,
pubmed-meshheading:10382577-Periodontal Diseases,
pubmed-meshheading:10382577-Periodontal Index,
pubmed-meshheading:10382577-Prognosis,
pubmed-meshheading:10382577-Regression Analysis,
pubmed-meshheading:10382577-Risk Factors,
pubmed-meshheading:10382577-Smoking,
pubmed-meshheading:10382577-Socioeconomic Factors,
pubmed-meshheading:10382577-Tooth Loss
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pubmed:year |
1999
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pubmed:articleTitle |
Longitudinal study of predictive factors for periodontal disease and tooth loss.
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pubmed:affiliation |
Periodontal Disease Research Center, Department of Oral Biology, School of Dental Medicine, State University of New York at Buffalo, 14214, USA. Machtei@rambam.health.gov.il
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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