Linked Life Data

10380568

Source:http://linkedlifedata.com/resource/pubmed/id/10380568

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1999-7-27
pubmed:abstractText
We studied the serum levels of IL-2, IFN-gamma and TNF in different clinical forms of Chagas' disease and in patients clinically compensated and decompensated. Cytokines measured in 91 patients with the chronic form of the disease did not differ from those of 13 normal individuals, suggesting the absence of activation of the TH1 pattern of lymphocyte response. There were no statistical differences among the 17 patients in the indeterminate form of the disease, the patients presenting either early (n = 4) or well-developed signs of cardiomyopathy (n = 62), the digestive (n = 4) or the mixed (n = 4) forms of the disease. Serum TNF was undetectable and IFN-gamma levels did not differ between clinical forms and severities of Chagas' disease. However, we found IL-2 higher levels in the 25 non-controlled patients than in the 66 controlled individuals (p < 0.001). We suggest that IL-2 dosage may be useful as an indicator of the need for more aggressive procedures.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0037-8682
pubmed:author
pubmed:issnType
Print
pubmed:volume
32
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
285-9
pubmed:dateRevised
2008-11-21
pubmed:meshHeading
pubmed:articleTitle
Serum cytokines in chronic Chagas' disease.
pubmed:affiliation
Department of Medicine, Faculty of Medical Sciences, State University of Campinas (UNICAMP), São Paulo, Brazil. Ward@TURING.UNICAMP.BR
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't